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    cdc7 cell division cycle 7 homolog (S. cerevisiae) [ Danio rerio (zebrafish) ]

    Gene ID: 492768, updated on 27-Mar-2024

    Summary

    Official Symbol
    cdc7provided by ZNC
    Official Full Name
    cell division cycle 7 homolog (S. cerevisiae)provided by ZNC
    Primary source
    ZFIN:ZDB-GENE-041114-113
    See related
    Ensembl:ENSDARG00000023584 AllianceGenome:ZFIN:ZDB-GENE-041114-113
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    im:7138214; zgc:101602
    Summary
    Predicted to enable protein serine/threonine kinase activity. Predicted to be involved in double-strand break repair via break-induced replication and peptidyl-serine phosphorylation. Predicted to act upstream of or within protein phosphorylation. Predicted to be active in cytoplasm and nucleus. Orthologous to human CDC7 (cell division cycle 7). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    See cdc7 in Genome Data Viewer
    Location:
    chromosome: 2
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 2 NC_007113.7 (10863941..10877769, complement)
    105 previous assembly GRCz10 (GCF_000002035.5) 2 NC_007113.6 (11080352..11094171, complement)

    Chromosome 2 - NC_007113.7Genomic Context describing neighboring genes Neighboring gene growth factor independent 1A transcription repressor a Neighboring gene RNA polymerase II associated protein 2 Neighboring gene glomulin, FKBP associated protein a Neighboring gene transcription elongation factor A (SII) N-terminal and central domain containing 2 Neighboring gene CUB domain containing protein 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in double-strand break repair via break-induced replication IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in peptidyl-serine phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    cell division cycle 7-related protein kinase
    NP_001007410.1
    XP_005171217.1
    XP_005171218.1
    XP_005171219.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001007409.1NP_001007410.1  cell division cycle 7-related protein kinase

      See identical proteins and their annotated locations for NP_001007410.1

      Status: PROVISIONAL

      Source sequence(s)
      BC085380
      UniProtKB/TrEMBL
      Q5U3V5
      Related
      ENSDARP00000091380.3, ENSDART00000100607.6
      Conserved Domains (2) summary
      smart00220
      Location:46332
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14019
      Location:45341
      STKc_Cdc7; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 7 kinase

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007113.7 Reference GRCz11 Primary Assembly

      Range
      10863941..10877769 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005171162.4XP_005171219.1  cell division cycle 7-related protein kinase isoform X3

      UniProtKB/TrEMBL
      A0A8M2BID8, B0UYH9
      Related
      ENSDARP00000118103.1, ENSDART00000138718.3
      Conserved Domains (2) summary
      smart00220
      Location:46364
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14019
      Location:45373
      STKc_Cdc7; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 7 kinase
    2. XM_005171161.4XP_005171218.1  cell division cycle 7-related protein kinase isoform X2

      UniProtKB/TrEMBL
      A0A8M2BIV6
      Conserved Domains (3) summary
      smart00220
      Location:46390
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14019
      Location:45399
      STKc_Cdc7; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 7 kinase
      cl21453
      Location:300481
      PKc_like; Protein Kinases, catalytic domain
    3. XM_005171160.4XP_005171217.1  cell division cycle 7-related protein kinase isoform X1

      UniProtKB/TrEMBL
      A0A8M2BIF5, B0UYI0
      Related
      ENSDARP00000032739.5, ENSDART00000034246.6
      Conserved Domains (2) summary
      cd14019
      Location:45431
      STKc_Cdc7; Catalytic domain of the Serine/Threonine Kinase, Cell Division Cycle 7 kinase
      cl21453
      Location:332513
      PKc_like; Protein Kinases, catalytic domain