U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Links from GEO Profiles

    • Showing Current items.

    acin1b apoptotic chromatin condensation inducer 1b [ Danio rerio (zebrafish) ]

    Gene ID: 327495, updated on 27-Mar-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    acin1bprovided by ZNC
    Official Full Name
    apoptotic chromatin condensation inducer 1bprovided by ZNC
    Primary source
    ZFIN:ZDB-GENE-030826-12
    See related
    Ensembl:ENSDARG00000026842 AllianceGenome:ZFIN:ZDB-GENE-030826-12
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Danio rerio
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Cypriniformes; Danionidae; Danioninae; Danio
    Also known as
    acinus; acinusb; fi14c05; wu:fe06a10; wu:fi14c05
    Summary
    Predicted to enable nucleic acid binding activity. Orthologous to human ACIN1 (apoptotic chromatin condensation inducer 1). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
    all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    See acin1b in Genome Data Viewer
    Location:
    chromosome: 7
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current GRCz11 (GCF_000002035.6) 7 NC_007118.7 (24069328..24097012)
    105 previous assembly GRCz10 (GCF_000002035.5) 7 NC_007118.6 (23798167..23825102)

    Chromosome 7 - NC_007118.7Genomic Context describing neighboring genes Neighboring gene dehydrogenase/reductase (SDR family) member 4 Neighboring gene embryonal Fyn-associated substrate Neighboring gene ajuba LIM protein Neighboring gene mitochondrial ribosomal protein L52

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • Description: Sequencing the Zebrafish transcriptome from a range of tissues and developmental stages
    • BioProject: PRJEB1986
    • Analysis date: Fri Dec 8 19:48:10 2017

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. MNK2 deficiency potentiates β-cell regeneration via translational regulation. Karampelias C, et al. Nat Chem Biol, 2022 Sep. PMID 35697798, Free PMC Article
    2. Genes with homology to mammalian apoptosis regulators identified in zebrafish. Inohara N, et al. Cell Death Differ, 2000 May. PMID 10917738
    3. Processing of fish Ig heavy chain transcripts: diverse splicing patterns and unusual nonsense mediated decay. Quiniou SM, et al. Dev Comp Immunol, 2011 Sep. PMID 21168434
    4. The zebrafish gene map defines ancestral vertebrate chromosomes. Woods IG, et al. Genome Res, 2005 Sep. PMID 16109975, Free PMC Article
    5. RFX transcription factors are essential for hearing in mice. Elkon R, et al. Nat Commun, 2015 Oct 15. PMID 26469318, Free PMC Article

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Gene Ontology Provided by ZFIN

    Function Evidence Code Pubs
    enables nucleic acid binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in RNA splicing IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of ASAP complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    apoptotic chromatin condensation inducer 1b; apoptotic chromatin condensation inducer in the nucleus
    Names
    apoptotic chromatin condensation inducer in the nucleus, b

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001305582.1 → NP_001292511.1  apoptotic chromatin condensation inducer 1b

      Status: VALIDATED

      Source sequence(s)
      CR388231, CT027785
      UniProtKB/TrEMBL
      A0A8M1P1U4, F1Q511
      Related
      ENSDARP00000029637.6, ENSDART00000034218.9
      Conserved Domains (3) summary
      cd12432
      Location:912 → 998
      RRM_ACINU; RNA recognition motif in apoptotic chromatin condensation inducer in the nucleus (acinus) and similar proteins
      pfam02037
      Location:14 → 48
      SAP; SAP domain
      pfam16294
      Location:1122 → 1157
      RSB_motif; RNSP1-SAP18 binding (RSB) motif

    RefSeqs of Annotated Genomes: Danio rerio Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCz11 Primary Assembly

    Genomic

    1. NC_007118.7 Reference GRCz11 Primary Assembly

      Range
      24069328..24097012
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_021477409.1 → XP_021333084.1  apoptotic chromatin condensation inducer in the nucleus isoform X1

      UniProtKB/TrEMBL
      A0A8M9Q7J4
      Conserved Domains (3) summary
      cd12432
      Location:265 → 351
      RRM_ACINU; RNA recognition motif in apoptotic chromatin condensation inducer in the nucleus (acinus) and similar proteins
      pfam16294
      Location:475 → 510
      RSB_motif; RNSP1-SAP18 binding (RSB) motif
      cl28310
      Location:495 → 611
      Rho; Transcription termination factor Rho [Transcription]

    2. XM_021477410.1 → XP_021333085.1  apoptotic chromatin condensation inducer in the nucleus isoform X2

      UniProtKB/TrEMBL
      A0A8M9QGN5
      Conserved Domains (3) summary
      cd12432
      Location:212 → 298
      RRM_ACINU; RNA recognition motif in apoptotic chromatin condensation inducer in the nucleus (acinus) and similar proteins
      pfam16294
      Location:422 → 457
      RSB_motif; RNSP1-SAP18 binding (RSB) motif
      cl28310
      Location:442 → 558
      Rho; Transcription termination factor Rho [Transcription]

    RNA

    1. XR_224930.4 RNA Sequence

    2. XR_002459127.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Molecular Biology Databases
    Research Materials
    Tools