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    Qrfprl pyroglutamylated RFamide peptide receptor like [ Mus musculus (house mouse) ]

    Gene ID: 243407, updated on 11-Apr-2024

    Summary

    Official Symbol
    Qrfprlprovided by MGI
    Official Full Name
    pyroglutamylated RFamide peptide receptor likeprovided by MGI
    Primary source
    MGI:MGI:2441881
    See related
    Ensembl:ENSMUSG00000029917 AllianceGenome:MGI:2441881
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C130060K24Rik
    Summary
    Predicted to enable G protein-coupled receptor activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to be integral component of plasma membrane. Is expressed in several structures, including brain; cardiovascular system; cranium; limb; and urinary system. Orthologous to human QRFPR (pyroglutamylated RFamide peptide receptor). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in ovary adult (RPKM 1.4), CNS E11.5 (RPKM 0.5) and 5 other tissues See more
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    Genomic context

    See Qrfprl in Genome Data Viewer
    Location:
    6 C1; 6 30.19 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (65358278..65435134)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (65381294..65458150)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_16135 Neighboring gene predicted gene, 20177 Neighboring gene VISTA enhancer mm1557 Neighboring gene thiopurine S-methyltransferase pseudogene Neighboring gene zinc finger CCCH type containing 14 pseudogene Neighboring gene DnaJ (Hsp40) homolog, subfamily C, member 2 pseudogene Neighboring gene STARR-seq mESC enhancer starr_16136 Neighboring gene predicted gene, 50629 Neighboring gene STARR-positive B cell enhancer ABC_E6434 Neighboring gene STARR-positive B cell enhancer mm9_chr6:65544132-65544433 Neighboring gene TNFAIP3 interacting protein 3

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables G protein-coupled receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables G protein-coupled receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables peptide binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in G protein-coupled receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in G protein-coupled receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to hormone stimulus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    uncharacterized protein LOC243407

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_175524.4NP_780733.2  uncharacterized protein LOC243407

      See identical proteins and their annotated locations for NP_780733.2

      Status: VALIDATED

      Source sequence(s)
      AK048439, AK051723, BB632079
      Consensus CDS
      CCDS20206.2
      UniProtKB/TrEMBL
      G3UWA8, Q8BHH0
      Related
      ENSMUSP00000130225.2, ENSMUST00000170608.8
      Conserved Domains (2) summary
      pfam00001
      Location:61331
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:55175
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      65358278..65435134
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)