Tatdn2 TatD DNase domain containing 2 [Rattus norvegicus (Norway rat)] - Gene

Summary

Official Symbol: Tatdn2provided by RGD
Official Full Name: TatD DNase domain containing 2provided by RGD
Primary source: RGD:1586017
See related: Ensembl:ENSRNOG00000042482 AllianceGenome:RGD:1586017
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Summary: Predicted to enable hydrolase activity, acting on ester bonds. Orthologous to human TATDN2 (TatD DNase domain containing 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in Heart (RPKM 166.5), Kidney (RPKM 143.0) and 9 other tissues See more
Orthologs: human mouse all
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Genomic context

Location:: 4q42

Exon count:: 9

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	4	NC_086022.1 (148400454..148416501)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	4	NC_051339.1 (146845156..146865708)
106	previous assembly	Rnor_6.0 (GCF_000001895.5)	4	NC_005103.4 (145653299..145669343)

Chromosome 4 - NC_086022.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
BioProject: PRJNA238328
Publication: PMID 24510058
Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Markers

RH143482 (e-PCR)
- UniSTS:232729

AU048121 (e-PCR)
- UniSTS:109851

RH139061 (e-PCR)
- UniSTS:221147

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables hydrolase activity, acting on ester bonds	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: putative deoxyribonuclease TATDN2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001109252.1 → NP_001102722.1 putative deoxyribonuclease TATDN2

See identical proteins and their annotated locations for NP_001102722.1

Status: PROVISIONAL

Source sequence(s)

CH473957

UniProtKB/TrEMBL

A6IBT8, D3ZT26

Related

ENSRNOP00000030898.5, ENSRNOT00000038964.5

Conserved Domains (2) summary

COG1099
Location:507 → 773

COG1099; Predicted metal-dependent hydrolase, TIM-barrel fold [General function prediction only]

pfam01026
Location:508 → 772

TatD_DNase; TatD related DNase