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    Lkaaear1 LKAAEAR motif containing 1 (IKAAEAR murine motif) [ Mus musculus (house mouse) ]

    Gene ID: 277496, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Lkaaear1provided by MGI
    Official Full Name
    LKAAEAR motif containing 1 (IKAAEAR murine motif)provided by MGI
    Primary source
    MGI:MGI:2685538
    See related
    Ensembl:ENSMUSG00000045794 AllianceGenome:MGI:2685538
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm692; 4930526D03Rik
    Summary
    Orthologous to human LKAAEAR1 (LKAAEAR motif containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 83.1) See more
    Orthologs
    human all
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    Genomic context

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    Location:
    2 H4; 2 103.73 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (181338586..181340235, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (181696793..181698442, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene transcription elongation factor A (SII), 2 Neighboring gene regulator of G-protein signaling 19 Neighboring gene STARR-positive B cell enhancer mm9_chr2:181441345-181441645 Neighboring gene opioid receptor-like 1 Neighboring gene neuropeptides B/W receptor 2 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
    2. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    3. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    4. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article
    5. Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. Carninci P, et al. Genome Res, 2000 Oct. PMID 11042159, Free PMC Article

    See all (9) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein LKAAEAR1
    Names
    LKAAEAR motif-containing protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001378943.1 → NP_001365872.1  protein LKAAEAR1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL845173
      Conserved Domains (1) summary
      pfam15478
      Location:44 → 179
      LKAAEAR; Family of unknown function with LKAAEAR motif

    2. NM_199023.3 → NP_950188.2  protein LKAAEAR1 isoform 2

      See identical proteins and their annotated locations for NP_950188.2

      Status: VALIDATED

      Source sequence(s)
      AK076877, BC087873
      Consensus CDS
      CCDS17221.1
      UniProtKB/Swiss-Prot
      Q5I0W3, Q8BIG2
      Related
      ENSMUSP00000061134.4, ENSMUST00000052416.4
      Conserved Domains (1) summary
      pfam15478
      Location:44 → 179
      LKAAEAR; Family of unknown function with LKAAEAR motif

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      181338586..181340235 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030251720.1 → XP_030107580.1  protein LKAAEAR1 isoform X4

      Conserved Domains (1) summary
      pfam15478
      Location:44 → 179
      LKAAEAR; Family of unknown function with LKAAEAR motif

    2. XM_030251704.1 → XP_030107564.1  protein LKAAEAR1 isoform X1

      Conserved Domains (1) summary
      pfam15478
      Location:62 → 197
      LKAAEAR; Family of unknown function with LKAAEAR motif

    3. XM_006500655.3 → XP_006500718.1  protein LKAAEAR1 isoform X6

      Conserved Domains (1) summary
      pfam15478
      Location:62 → 197
      LKAAEAR; Family of unknown function with LKAAEAR motif

    4. XM_006500654.1 → XP_006500717.1  protein LKAAEAR1 isoform X5

      Conserved Domains (1) summary
      pfam15478
      Location:62 → 197
      LKAAEAR; Family of unknown function with LKAAEAR motif

    5. XM_030251721.1 → XP_030107581.1  protein LKAAEAR1 isoform X4

      Conserved Domains (1) summary
      pfam15478
      Location:44 → 179
      LKAAEAR; Family of unknown function with LKAAEAR motif

    6. XM_030251707.1 → XP_030107567.1  protein LKAAEAR1 isoform X3

      Conserved Domains (1) summary
      pfam15478
      Location:55 → 190
      LKAAEAR; Family of unknown function with LKAAEAR motif

    7. XM_006500657.2 → XP_006500720.1  protein LKAAEAR1 isoform X7

      See identical proteins and their annotated locations for XP_006500720.1

      Conserved Domains (1) summary
      pfam15478
      Location:55 → 190
      LKAAEAR; Family of unknown function with LKAAEAR motif

    8. XM_030251705.1 → XP_030107565.1  protein LKAAEAR1 isoform X2

      Conserved Domains (1) summary
      pfam15478
      Location:48 → 183
      LKAAEAR; Family of unknown function with LKAAEAR motif
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BIG2.2 GenPept UniProtKB/Swiss-Prot:Q8BIG2

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