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    Vstm2b V-set and transmembrane domain containing 2B [ Mus musculus (house mouse) ]

    Gene ID: 58188, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Vstm2bprovided by MGI
    Official Full Name
    V-set and transmembrane domain containing 2Bprovided by MGI
    Primary source
    MGI:MGI:1914525
    See related
    Ensembl:ENSMUSG00000039257 AllianceGenome:MGI:1914525
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2900093B09Rik
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in brain and spinal cord mantle layer. Orthologous to human VSTM2B (V-set and transmembrane domain containing 2B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in stomach adult (RPKM 77.8), CNS E18 (RPKM 26.6) and 10 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    7 B3; 7 27.88 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (40547614..40579468)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (40898011..40930044)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA A230077H06 gene Neighboring gene predicted gene, 25784 Neighboring gene predicted gene, 51479 Neighboring gene RIKEN cDNA 4930433I11 gene Neighboring gene predicted gene, 38997 Neighboring gene STARR-seq mESC enhancer starr_18725

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Transcriptomic analysis and novel insights into lens fibre cell differentiation regulated by Gata3. Martynova E, et al. Open Biol, 2019 Dec. PMID 31847788, Free PMC Article
    2. Growth suppression of Escherichia coli by induction of expression of mammalian genes with transmembrane or ATPase domains. Inoue S, et al. Biochem Biophys Res Commun, 2000 Feb 16. PMID 10679242
    3. Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. Gu Z, et al. PLoS One, 2015. PMID 25826454, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (12) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    V-set and transmembrane domain-containing protein 2B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001418631.1 → NP_001405560.1  V-set and transmembrane domain-containing protein 2B isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC136717

    2. NM_001418632.1 → NP_001405561.1  V-set and transmembrane domain-containing protein 2B isoform 3 precursor

      Status: VALIDATED

      Source sequence(s)
      AC136717

    3. NM_001418634.1 → NP_001405563.1  V-set and transmembrane domain-containing protein 2B isoform 1 precursor

      Status: VALIDATED

      Source sequence(s)
      AC136717
      UniProtKB/Swiss-Prot
      Q8CEK5, Q9JME9
      Related
      ENSMUSP00000044002.10, ENSMUST00000044705.12

    4. NM_001418635.1 → NP_001405564.1  V-set and transmembrane domain-containing protein 2B isoform 2 precursor

      Status: VALIDATED

      Source sequence(s)
      AC136717

    5. NM_021387.4 → NP_067362.1  V-set and transmembrane domain-containing protein 2B isoform 1 precursor

      See identical proteins and their annotated locations for NP_067362.1

      Status: VALIDATED

      Source sequence(s)
      AC136717
      Consensus CDS
      CCDS21160.1
      UniProtKB/Swiss-Prot
      Q8CEK5, Q9JME9
      Related
      ENSMUSP00000146231.2, ENSMUST00000205845.2
      Conserved Domains (1) summary
      smart00410
      Location:34 → 148
      IG_like; Immunoglobulin like

    RNA

    1. NR_184788.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC136717

    2. NR_184789.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AC136717

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      40547614..40579468
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006541032.5 → XP_006541095.1  V-set and transmembrane domain-containing protein 2B isoform X2

      Conserved Domains (1) summary
      smart00409
      Location:34 → 178
      IG; Immunoglobulin
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9JME9.1 GenPept UniProtKB/Swiss-Prot:Q9JME9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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