Rbfox2 RNA binding protein, fox-1 homolog (C. elegans) 2 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Rbfox2provided by MGI
Official Full Name: RNA binding protein, fox-1 homolog (C. elegans) 2provided by MGI
Primary source: MGI:MGI:1933973
See related: Ensembl:ENSMUSG00000033565 AllianceGenome:MGI:1933973
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Fxh; Fbm2; Rbm9; Hrnbp2
Summary: Enables mRNA binding activity. Involved in regulation of alternative mRNA splicing, via spliceosome and regulation of definitive erythrocyte differentiation. Acts upstream of or within several processes, including alternative mRNA splicing, via spliceosome; nervous system development; and regulation of heart rate by cardiac conduction. Located in nucleus. Is expressed in several structures, including blastocyst; brain; dorsal root ganglion; early embryo; and limb. Orthologous to human RBFOX2 (RNA binding fox-1 homolog 2). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Broad expression in CNS E18 (RPKM 47.2), whole brain E14.5 (RPKM 43.2) and 25 other tissues See more
Orthologs: human all
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Genomic context

Location:: 15 D3; 15 36.4 cM

Exon count:: 23

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	15	NC_000081.7 (76963190..77193058, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	15	NC_000081.6 (77078990..77308434, complement)

Chromosome 15 - NC_000081.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Modulation of insulin secretion by RBFOX2-mediated alternative splicing.
Title: Modulation of insulin secretion by RBFOX2-mediated alternative splicing.
Suppression of RBFox2 by Multiple MiRNAs in Pressure Overload-Induced Heart Failure.
Title: Suppression of RBFox2 by Multiple MiRNAs in Pressure Overload-Induced Heart Failure.
Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice.
Title: Liver RBFOX2 regulates cholesterol homeostasis via Scarb1 alternative splicing in mice.
RBFOX2 is required for establishing RNA regulatory networks essential for heart development.
Title: RBFOX2 is required for establishing RNA regulatory networks essential for heart development.
Expression of the alternative splicing regulator Rbfox2 during placental development is differentially regulated in preeclampsia mouse models.
Title: Expression of the alternative splicing regulator Rbfox2 during placental development is differentially regulated in preeclampsia mouse models.
The effect of Rbfox2 modulation on retinal transcriptome and visual function.
Title: The effect of Rbfox2 modulation on retinal transcriptome and visual function.
Concentration-dependent splicing is enabled by Rbfox motifs of intermediate affinity.
Title: Concentration-dependent splicing is enabled by Rbfox motifs of intermediate affinity.
Expression of Rbfox2 is essential for proper exon splicing of genes of the cGMP-PKG-Ca2+ pathway.
Title: Genes of the cGMP-PKG-Ca(2+) signaling pathway are alternatively spliced in cardiomyopathy: Role of RBFOX2.
Here, the authors demonstrate that splicing factor Rbfox2 is expressed in the neural crest cells (NCCs), and deletion of Rbfox2 in NCCs leads to cleft palate and defects in craniofacial bone development. RNA-Seq analysis revealed that Rbfox2 regulates splicing and expression of numerous genes essential for neural crest/craniofacial development.
Title: Neural crest-specific deletion of Rbfox2 in mice leads to craniofacial abnormalities including cleft palate.
Rbfox deletion did not cause a reduction in global protein synthesis, but it led to altered splicing of hundreds of gene transcripts, including capn3, which produced an active form of calpain3 protease.
Title: Rbfox-Splicing Factors Maintain Skeletal Muscle Mass by Regulating Calpain3 and Proteostasis.

Submit: New GeneRIF Correction See all GeneRIFs (24)

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Gene trapped (1) 1 citation
Targeted (1)
Endonuclease-mediated (5) 1 citation

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

D15Mit146 (e-PCR), detects polymorphism
- UniSTS:127508

AI118529 (e-PCR)
- UniSTS:180777

RH125552 (e-PCR)
- UniSTS:162366

RH11177 (e-PCR)
- UniSTS:84549

02.MMHAP17FA2.seq (e-PCR)
- UniSTS:122697

R75115 (e-PCR)
- UniSTS:125536

RH125714 (e-PCR)
- UniSTS:162477

AU021833 (e-PCR)
- UniSTS:209103

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables DNA-binding transcription factor binding	ISO Inferred from Sequence Orthology more info
enables RNA binding	ISO Inferred from Sequence Orthology more info
enables RNA binding	ISS Inferred from Sequence or Structural Similarity more info	PubMed
enables mRNA binding	IBA Inferred from Biological aspect of Ancestor more info
enables mRNA binding	IDA Inferred from Direct Assay more info	PubMed
enables nucleic acid binding	IEA Inferred from Electronic Annotation more info
enables protein binding	IPI Inferred from Physical Interaction more info	PubMed
enables single-stranded RNA binding	ISO Inferred from Sequence Orthology more info
enables transcription corepressor activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within RNA splicing	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within dendrite morphogenesis	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in intracellular estrogen receptor signaling pathway	ISO Inferred from Sequence Orthology more info
involved_in mRNA alternative polyadenylation	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within mRNA processing	IEA Inferred from Electronic Annotation more info
involved_in negative regulation of DNA-templated transcription	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of apoptotic process	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of membrane hyperpolarization	ISO Inferred from Sequence Orthology more info
involved_in negative regulation of mitochondrial depolarization	ISO Inferred from Sequence Orthology more info
involved_in nervous system development	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within neuromuscular process controlling balance	IGI Inferred from Genetic Interaction more info	PubMed
involved_in positive regulation of gene expression	ISO Inferred from Sequence Orthology more info
involved_in positive regulation of vasoconstriction	ISO Inferred from Sequence Orthology more info
acts_upstream_of_or_within radial glia guided migration of Purkinje cell	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of RNA splicing	IEA Inferred from Electronic Annotation more info
involved_in regulation of alternative mRNA splicing, via spliceosome	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within regulation of alternative mRNA splicing, via spliceosome	IGI Inferred from Genetic Interaction more info	PubMed
acts_upstream_of_or_within regulation of alternative mRNA splicing, via spliceosome	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of alternative mRNA splicing, via spliceosome	IMP Inferred from Mutant Phenotype more info	PubMed
involved_in regulation of alternative mRNA splicing, via spliceosome	ISO Inferred from Sequence Orthology more info
involved_in regulation of definitive erythrocyte differentiation	IDA Inferred from Direct Assay more info	PubMed
involved_in regulation of mitochondrial gene expression	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
is_active_in cytoplasm	IBA Inferred from Biological aspect of Ancestor more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in nucleoplasm	ISO Inferred from Sequence Orthology more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info
located_in nucleus	IDA Inferred from Direct Assay more info	PubMed
located_in nucleus	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: RNA binding protein fox-1 homolog 2

Names: Fyn-binding molecule 2; RNA-binding motif protein 9; fox-1 homolog B; fox-1 homolog Fxh; hexaribonucleotide-binding protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001110827.3 → NP_001104297.1 RNA binding protein fox-1 homolog 2 isoform 3

Status: VALIDATED

Source sequence(s)

AL591892, AL603843, AL772386

UniProtKB/Swiss-Prot

Q8BP71

Conserved Domains (3) summary

cd12407
Location:180 → 255

RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins

TIGR01661
Location:37 → 251

ELAV_HUD_SF; ELAV/HuD family splicing factor

pfam12414
Location:320 → 417

Fox-1_C; Calcitonin gene-related peptide regulator C terminal
NM_001110828.3 → NP_001104298.1 RNA binding protein fox-1 homolog 2 isoform 4

See identical proteins and their annotated locations for NP_001104298.1

Status: VALIDATED

Source sequence(s)

AL603843

Consensus CDS

CCDS49658.1

UniProtKB/Swiss-Prot

Q8BP71

Conserved Domains (3) summary

cd12407
Location:112 → 187

RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins

pfam12414
Location:256 → 353

Fox-1_C; Calcitonin gene-related peptide regulator C terminal

cl25887
Location:96 → 262

RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]
NM_001110829.3 → NP_001104299.1 RNA binding protein fox-1 homolog 2 isoform 5

See identical proteins and their annotated locations for NP_001104299.1

Status: VALIDATED

Source sequence(s)

AL603843

Consensus CDS

CCDS49657.1

UniProtKB/Swiss-Prot

Q8BP71

Related

ENSMUSP00000154233.2, ENSMUST00000227314.2

Conserved Domains (2) summary

cd12407
Location:112 → 187

RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins

pfam12414
Location:252 → 350

Fox-1_C; Calcitonin gene-related peptide regulator C terminal
NM_001110830.3 → NP_001104300.1 RNA binding protein fox-1 homolog 2 isoform 6

See identical proteins and their annotated locations for NP_001104300.1

Status: VALIDATED

Source sequence(s)

AL603843

Consensus CDS

CCDS88798.1

UniProtKB/Swiss-Prot

Q8BP71

Related

ENSMUSP00000153751.2, ENSMUST00000228087.2

Conserved Domains (3) summary

TIGR01645
Location:96 → 248

half-pint; poly-U binding splicing factor, half-pint family

cd12407
Location:112 → 187

RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins

pfam12414
Location:252 → 349

Fox-1_C; Calcitonin gene-related peptide regulator C terminal
NM_001286417.2 → NP_001273346.1 RNA binding protein fox-1 homolog 2 isoform 7

Status: VALIDATED

Source sequence(s)

AL603843

Consensus CDS

CCDS88797.1

UniProtKB/TrEMBL

A0A2K6EDK7

Related

ENSMUSP00000129372.3, ENSMUST00000111581.4

Conserved Domains (2) summary

cd12407
Location:112 → 187

RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins

pfam12414
Location:252 → 300

Fox-1_C; Calcitonin gene-related peptide regulator C terminal
NM_001286418.2 → NP_001273347.1 RNA binding protein fox-1 homolog 2 isoform 8

See identical proteins and their annotated locations for NP_001273347.1

Status: VALIDATED

Source sequence(s)

AL603843

Consensus CDS

CCDS88795.1

UniProtKB/Swiss-Prot

Q8BP71

Related

ENSMUSP00000154810.2, ENSMUST00000227930.2

Conserved Domains (1) summary

pfam12414
Location:158 → 255

Fox-1_C; Calcitonin gene-related peptide regulator C terminal
NM_001286419.2 → NP_001273348.1 RNA binding protein fox-1 homolog 2 isoform 9

See identical proteins and their annotated locations for NP_001273348.1

Status: VALIDATED

Source sequence(s)

AL603843

Consensus CDS

CCDS88796.1

UniProtKB/Swiss-Prot

Q8BP71

Related

ENSMUSP00000154209.2, ENSMUST00000227533.2

Conserved Domains (3) summary

COG0724
Location:70 → 145

RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

pfam12414
Location:220 → 318

Fox-1_C; Calcitonin gene-related peptide regulator C terminal

cl17169
Location:111 → 150

RRM_SF; RNA recognition motif (RRM) superfamily
NM_001358770.2 → NP_001345699.1 RNA binding protein fox-1 homolog 2 isoform 10

Status: VALIDATED

Source sequence(s)

AL591892, AL603843

Conserved Domains (3) summary

TIGR01645
Location:118 → 270

half-pint; poly-U binding splicing factor, half-pint family

cd12407
Location:134 → 209

RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins

pfam12414
Location:274 → 371

Fox-1_C; Calcitonin gene-related peptide regulator C terminal
NM_001358772.2 → NP_001345701.1 RNA binding protein fox-1 homolog 2 isoform 12

Status: VALIDATED

Source sequence(s)

AL591892, AL603843

Conserved Domains (2) summary

cd12407
Location:134 → 209

RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins

pfam12414
Location:274 → 331

Fox-1_C; Calcitonin gene-related peptide regulator C terminal
NM_001412007.1 → NP_001398936.1 RNA binding protein fox-1 homolog 2 isoform 13

Status: VALIDATED

Source sequence(s)

AL591892, AL603843, AL772386
NM_001412008.1 → NP_001398937.1 RNA binding protein fox-1 homolog 2 isoform 14

Status: VALIDATED

Source sequence(s)

AL591892, AL603843, AL772386
NM_001412009.1 → NP_001398938.1 RNA binding protein fox-1 homolog 2 isoform 15

Status: VALIDATED

Source sequence(s)

AL603843, AL772386
NM_001412010.1 → NP_001398939.1 RNA binding protein fox-1 homolog 2 isoform 16

Status: VALIDATED

Source sequence(s)

AL603843, AL772386
NM_001412011.1 → NP_001398940.1 RNA binding protein fox-1 homolog 2 isoform 37

Status: VALIDATED

Source sequence(s)

AL603843, AL772386
NM_001412012.1 → NP_001398941.1 RNA binding protein fox-1 homolog 2 isoform 17

Status: VALIDATED

Source sequence(s)

AL603843, AL772386
NM_001412013.1 → NP_001398942.1 RNA binding protein fox-1 homolog 2 isoform 18

Status: VALIDATED

Source sequence(s)

AL603843, AL772386
NM_001412014.1 → NP_001398943.1 RNA binding protein fox-1 homolog 2 isoform 19

Status: VALIDATED

Source sequence(s)

AL591892, AL603843
NM_001412015.1 → NP_001398944.1 RNA binding protein fox-1 homolog 2 isoform 20

Status: VALIDATED

Source sequence(s)

AL591892, AL603843
NM_001412016.1 → NP_001398945.1 RNA binding protein fox-1 homolog 2 isoform 21

Status: VALIDATED

Source sequence(s)

AL591892, AL603843
NM_001412017.1 → NP_001398946.1 RNA binding protein fox-1 homolog 2 isoform 22

Status: VALIDATED

Source sequence(s)

AL591892, AL603843
NM_001412018.1 → NP_001398947.1 RNA binding protein fox-1 homolog 2 isoform 23

Status: VALIDATED

Source sequence(s)

AL591892, AL603843
NM_001412019.1 → NP_001398948.1 RNA binding protein fox-1 homolog 2 isoform 24

Status: VALIDATED

Source sequence(s)

AL591892, AL603843
NM_001412020.1 → NP_001398949.1 RNA binding protein fox-1 homolog 2 isoform 25

Status: VALIDATED

Source sequence(s)

AL591892, AL603843
NM_001412021.1 → NP_001398950.1 RNA binding protein fox-1 homolog 2 isoform 26

Status: VALIDATED

Source sequence(s)

AL591892, AL603843
NM_001412022.1 → NP_001398951.1 RNA binding protein fox-1 homolog 2 isoform 27

Status: VALIDATED

Source sequence(s)

AL603843
NM_001412023.1 → NP_001398952.1 RNA binding protein fox-1 homolog 2 isoform 28

Status: VALIDATED

Source sequence(s)

AL603843
NM_001412024.1 → NP_001398953.1 RNA binding protein fox-1 homolog 2 isoform 29

Status: VALIDATED

Source sequence(s)

AL603843
NM_001412025.1 → NP_001398954.1 RNA binding protein fox-1 homolog 2 isoform 30

Status: VALIDATED

Source sequence(s)

AL603843
NM_001412026.1 → NP_001398955.1 RNA binding protein fox-1 homolog 2 isoform 31

Status: VALIDATED

Source sequence(s)

AL603843
NM_001412027.1 → NP_001398956.1 RNA binding protein fox-1 homolog 2 isoform 38

Status: VALIDATED

Source sequence(s)

AL603843
NM_001412028.1 → NP_001398957.1 RNA binding protein fox-1 homolog 2 isoform 32

Status: VALIDATED

Source sequence(s)

AL603843
NM_001412029.1 → NP_001398958.1 RNA binding protein fox-1 homolog 2 isoform 33

Status: VALIDATED

Source sequence(s)

AL603843
NM_001412030.1 → NP_001398959.1 RNA binding protein fox-1 homolog 2 isoform 34

Status: VALIDATED

Source sequence(s)

AL603843
NM_001412031.1 → NP_001398960.1 RNA binding protein fox-1 homolog 2 isoform 35

Status: VALIDATED

Source sequence(s)

AL603843
NM_001412032.1 → NP_001398961.1 RNA binding protein fox-1 homolog 2 isoform 36

Status: VALIDATED

Source sequence(s)

AL603843
NM_053104.7 → NP_444334.3 RNA binding protein fox-1 homolog 2 isoform 1

See identical proteins and their annotated locations for NP_444334.3

Status: VALIDATED

Source sequence(s)

AL591892, AL603843, AL772386

Consensus CDS

CCDS49659.1

UniProtKB/Swiss-Prot

Q0R5Z7, Q0R5Z8, Q0VH84, Q537D4, Q537D5, Q8BP71, Q8BRG0, Q8R2T5, Q8VI62, Q923W8

Related

ENSMUSP00000130739.2, ENSMUST00000171751.10

Conserved Domains (3) summary

cd12407
Location:180 → 255

RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins

TIGR01661
Location:37 → 251

ELAV_HUD_SF; ELAV/HuD family splicing factor

pfam12414
Location:324 → 421

Fox-1_C; Calcitonin gene-related peptide regulator C terminal
NM_175387.4 → NP_780596.1 RNA binding protein fox-1 homolog 2 isoform 2

See identical proteins and their annotated locations for NP_780596.1

Status: VALIDATED

Source sequence(s)

AL591892, AL603843, AL772386

Consensus CDS

CCDS27598.1

UniProtKB/Swiss-Prot

Q8BP71

Related

ENSMUSP00000048056.6, ENSMUST00000048145.13

Conserved Domains (2) summary

cd12407
Location:180 → 255

RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins

pfam12414
Location:320 → 368

Fox-1_C; Calcitonin gene-related peptide regulator C terminal

RNA

NR_177995.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AL603843
NR_177996.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AL603843
NR_177997.1 RNA Sequence

Status: VALIDATED

Source sequence(s)

AL603843

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000081.7 Reference GRCm39 C57BL/6J

Range

76963190..77193058 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_006521587.4 → XP_006521650.1 RNA binding protein fox-1 homolog 2 isoform X15

Conserved Domains (3) summary

COG0724
Location:138 → 213

RRM; RNA recognition motif (RRM) domain [Translation, ribosomal structure and biogenesis]

pfam12414
Location:288 → 386

Fox-1_C; Calcitonin gene-related peptide regulator C terminal

cl17169
Location:179 → 218

RRM_SF; RNA recognition motif (RRM) superfamily
XM_036159654.1 → XP_036015547.1 RNA binding protein fox-1 homolog 2 isoform X7

Conserved Domains (2) summary

pfam12414
Location:319 → 417

Fox-1_C; Calcitonin gene-related peptide regulator C terminal

cd12407
Location:179 → 254

RRM_FOX1_like; RNA recognition motif (RRM) found in vertebrate RNA binding protein fox-1 homologs and similar proteins
XM_006521570.4 → XP_006521633.1 RNA binding protein fox-1 homolog 2 isoform X4

Conserved Domains (2) summary

cd12407
Location:179 → 254

RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins

pfam12414
Location:319 → 376

Fox-1_C; Calcitonin gene-related peptide regulator C terminal
XM_036159656.1 → XP_036015549.1 RNA binding protein fox-1 homolog 2 isoform X18

Conserved Domains (2) summary

pfam12414
Location:289 → 337

Fox-1_C; Calcitonin gene-related peptide regulator C terminal

cl17169
Location:180 → 219

RRM_SF; RNA recognition motif (RRM) superfamily
XM_036159655.1 → XP_036015548.1 RNA binding protein fox-1 homolog 2 isoform X14

Conserved Domains (2) summary

pfam12414
Location:289 → 387

Fox-1_C; Calcitonin gene-related peptide regulator C terminal

cl17169
Location:180 → 219

RRM_SF; RNA recognition motif (RRM) superfamily
XM_006521576.4 → XP_006521639.1 RNA binding protein fox-1 homolog 2 isoform X6

Conserved Domains (3) summary

cd12407
Location:180 → 255

RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins

TIGR01661
Location:37 → 251

ELAV_HUD_SF; ELAV/HuD family splicing factor

pfam12414
Location:320 → 418

Fox-1_C; Calcitonin gene-related peptide regulator C terminal
XM_006521580.4 → XP_006521643.1 RNA binding protein fox-1 homolog 2 isoform X11

Conserved Domains (3) summary

TIGR01628
Location:168 → 421

PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family

cd12407
Location:180 → 255

RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins

pfam12414
Location:324 → 372

Fox-1_C; Calcitonin gene-related peptide regulator C terminal
XM_006521574.4 → XP_006521637.1 RNA binding protein fox-1 homolog 2 isoform X5

Conserved Domains (3) summary

cd12407
Location:180 → 255

RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins

TIGR01661
Location:37 → 251

ELAV_HUD_SF; ELAV/HuD family splicing factor

pfam12414
Location:324 → 422

Fox-1_C; Calcitonin gene-related peptide regulator C terminal
XM_006521568.4 → XP_006521631.1 RNA binding protein fox-1 homolog 2 isoform X1

Conserved Domains (3) summary

TIGR01645
Location:164 → 330

half-pint; poly-U binding splicing factor, half-pint family

cd12407
Location:180 → 255

RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins

pfam12414
Location:324 → 380

Fox-1_C; Calcitonin gene-related peptide regulator C terminal
XM_006521569.4 → XP_006521632.1 RNA binding protein fox-1 homolog 2 isoform X2

Conserved Domains (3) summary

TIGR01645
Location:164 → 330

half-pint; poly-U binding splicing factor, half-pint family

cd12407
Location:180 → 255

RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins

pfam12414
Location:324 → 381

Fox-1_C; Calcitonin gene-related peptide regulator C terminal
XM_030248852.2 → XP_030104712.1 RNA binding protein fox-1 homolog 2 isoform X36

UniProtKB/TrEMBL

A0A2I3BRU6

Related

ENSMUSP00000154522.2, ENSMUST00000228558.2

Conserved Domains (2) summary

cd12407
Location:134 → 209

RRM_FOX1_like; RNA recognition motif in vertebrate RNA binding protein fox-1 homologs and similar proteins

pfam12414
Location:274 → 318

Fox-1_C; Calcitonin gene-related peptide regulator C terminal

RNA

XR_003951446.2 RNA Sequence
XR_001781584.3 RNA Sequence
XR_384057.4 RNA Sequence
XR_004938883.1 RNA Sequence

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001358771.1: Suppressed sequence

Description

NM_001358771.1: This RefSeq was removed because currently there is insufficient support for the transcript and the protein.