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    Lrriq3 leucine-rich repeats and IQ motif containing 3 [ Mus musculus (house mouse) ]

    Gene ID: 74435, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Lrriq3provided by MGI
    Official Full Name
    leucine-rich repeats and IQ motif containing 3provided by MGI
    Primary source
    MGI:MGI:1921685
    See related
    Ensembl:ENSMUSG00000028182 AllianceGenome:MGI:1921685
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Lrrc44; 4930438B07Rik; 4930511J15Rik; 4933403H06Rik
    Summary
    Orthologous to human LRRIQ3 (leucine rich repeats and IQ motif containing 3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis adult (RPKM 6.7) and genital fat pad adult (RPKM 0.2) See more
    Orthologs
    human all
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    Genomic context

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    Location:
    3 H4; 3 79.54 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (154799032..154899915)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (155093395..155194278)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene TNNI3 interacting kinase Neighboring gene leucine rich repeat containing 4 pseudogene Neighboring gene STARR-seq mESC enhancer starr_09350 Neighboring gene STARR-seq mESC enhancer starr_09351 Neighboring gene STARR-seq mESC enhancer starr_09352 Neighboring gene STARR-seq mESC enhancer starr_09353 Neighboring gene STARR-positive B cell enhancer ABC_E7951 Neighboring gene fucose-1-phosphate guanylyltransferase Neighboring gene STARR-seq mESC enhancer starr_09354 Neighboring gene STARR-seq mESC enhancer starr_09355 Neighboring gene STARR-seq mESC enhancer starr_09356 Neighboring gene sperm motility kinase 3A pseudogene Neighboring gene STARR-seq mESC enhancer starr_09358 Neighboring gene sterol carrier protein 2, pseudogene 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC132959

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    leucine-rich repeat and IQ domain-containing protein 3
    Names
    leucine rich repeat containing 44
    leucine-rich repeat-containing protein 44

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_028938.2 → NP_083214.2  leucine-rich repeat and IQ domain-containing protein 3

      See identical proteins and their annotated locations for NP_083214.2

      Status: VALIDATED

      Source sequence(s)
      AK132656, BB019345, BY080708
      Consensus CDS
      CCDS38682.1
      UniProtKB/Swiss-Prot
      Q14DL3, Q9D4C3, Q9D562, Q9D5I0
      Related
      ENSMUSP00000029833.8, ENSMUST00000029833.13
      Conserved Domains (3) summary
      sd00031
      Location:52 → 73
      LRR_1; leucine-rich repeat [structural motif]
      pfam12252
      Location:459 → 630
      SidE; Dot/Icm substrate protein
      pfam13855
      Location:51 → 109
      LRR_8; Leucine rich repeat

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      154799032..154899915
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006502189.3 → XP_006502252.1  leucine-rich repeat and IQ domain-containing protein 3 isoform X1

      See identical proteins and their annotated locations for XP_006502252.1

      UniProtKB/Swiss-Prot
      Q14DL3, Q9D4C3, Q9D562, Q9D5I0
      Conserved Domains (3) summary
      sd00031
      Location:52 → 73
      LRR_1; leucine-rich repeat [structural motif]
      pfam12252
      Location:459 → 630
      SidE; Dot/Icm substrate protein
      pfam13855
      Location:51 → 109
      LRR_8; Leucine rich repeat

    2. XM_006502190.5 → XP_006502253.1  leucine-rich repeat and IQ domain-containing protein 3 isoform X2

      See identical proteins and their annotated locations for XP_006502253.1

      UniProtKB/Swiss-Prot
      Q14DL3
      Related
      ENSMUSP00000141372.2, ENSMUST00000192383.6
      Conserved Domains (2) summary
      sd00031
      Location:52 → 73
      LRR_1; leucine-rich repeat [structural motif]
      pfam13855
      Location:51 → 109
      LRR_8; Leucine rich repeat

    3. XM_017319774.3 → XP_017175263.1  leucine-rich repeat and IQ domain-containing protein 3 isoform X3

      Related
      ENSMUSP00000142127.2, ENSMUST00000194376.2
      Conserved Domains (2) summary
      sd00031
      Location:52 → 73
      LRR_1; leucine-rich repeat [structural motif]
      pfam13855
      Location:51 → 109
      LRR_8; Leucine rich repeat
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q14DL3.1 GenPept UniProtKB/Swiss-Prot:Q14DL3

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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