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    Retnlb resistin like beta [ Mus musculus (house mouse) ]

    Gene ID: 57263, updated on 21-Apr-2024

    Summary

    Official Symbol
    Retnlbprovided by MGI
    Official Full Name
    resistin like betaprovided by MGI
    Primary source
    MGI:MGI:1888505
    See related
    Ensembl:ENSMUSG00000022650 AllianceGenome:MGI:1888505
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Xcp3; Fizz2; Relmb; RELMbeta; 9030012B21Rik
    Summary
    Predicted to enable hormone activity. Acts upstream of or within response to bacterium. Located in extracellular region. Is expressed in cecum; colon; colon epithelium; embryo; and ileum. Orthologous to human RETNLB (resistin like beta). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward colon adult (RPKM 34.9) See more
    Orthologs
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    Genomic context

    Location:
    16 B5; 16 30.75 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (48637219..48639255)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (48816856..48818892)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene microrchidia 1 Neighboring gene STARR-seq mESC enhancer starr_40956 Neighboring gene STARR-seq mESC enhancer starr_40960 Neighboring gene predicted gene, 41458 Neighboring gene T cell receptor associated transmembrane adaptor 1 Neighboring gene TWIST neighbor pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr16:48788868-48789191 Neighboring gene resistin like alpha Neighboring gene resistin like gamma

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables hormone activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within response to bacterium IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in extracellular region IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in extracellular space IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    resistin-like beta
    Names
    cysteine-rich secreted protein A12-beta
    cysteine-rich secreted protein FIZZ2
    found in inflammatory zone 2
    resistin-like molecule beta

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_023881.4NP_076370.3  resistin-like beta precursor

      See identical proteins and their annotated locations for NP_076370.3

      Status: VALIDATED

      Source sequence(s)
      AF290871, AK020240
      Consensus CDS
      CCDS28210.1
      UniProtKB/Swiss-Prot
      Q99P86, Q9D286
      UniProtKB/TrEMBL
      A0A0R4J042
      Related
      ENSMUSP00000023328.7, ENSMUST00000023328.8
      Conserved Domains (1) summary
      pfam06954
      Location:23104
      Resistin; Resistin

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      48637219..48639255
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)