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    Ribc2 RIB43A domain with coiled-coils 2 [ Mus musculus (house mouse) ]

    Gene ID: 67747, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Ribc2provided by MGI
    Official Full Name
    RIB43A domain with coiled-coils 2provided by MGI
    Primary source
    MGI:MGI:1914997
    See related
    Ensembl:ENSMUSG00000022431 AllianceGenome:MGI:1914997
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Trib; 4930579A10Rik
    Summary
    Is expressed in bladder wall; diaphragm; ilio-psoas; skeleton; and tail mesenchyme. Orthologous to human RIBC2 (RIB43A domain with coiled-coils 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis adult (RPKM 6.1) and bladder adult (RPKM 0.1) See more
    Orthologs
    human all
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    Genomic context

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    Location:
    15 E2; 15 40.25 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (85016261..85028771)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (85132060..85144570)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 52194 Neighboring gene uroplakin 3A Neighboring gene family with sequence similarity 118, member A Neighboring gene STARR-seq mESC enhancer starr_39377 Neighboring gene structural maintenance of chromosomes 1B Neighboring gene ribosomal protein L23A pseudogene Neighboring gene predicted gene, 19277 Neighboring gene fibulin 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Genomic structure and expression analysis of the mouse testis-specific ribbon protein (Trib) gene. Arango NA, et al. Gene, 2004 Dec 8. PMID 15563848
    2. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    3. BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Pourhaghighi R, et al. Cell Syst, 2020 Apr 22. PMID 32325033, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). Gerhard DS, et al. Genome Res, 2004 Oct. PMID 15489334, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Genomic structure and expression profile of mouse Trib and comparison of its homology with other ribbon proteins.
      Title: Genomic structure and expression analysis of the mouse testis-specific ribbon protein (Trib) gene.
    2. Trib expression is testis-specific and appears to be found only in the germ cells during the leptotene-pachytene stages of spermatogenesis.
      Title: Genomic structure and expression analysis of the mouse testis-specific ribbon protein (Trib) gene.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC130587

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in axonemal A tubule inner sheath IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in axonemal microtubule ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    RIB43A-like with coiled-coils protein 2
    Names
    testis-specific ribbon protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026357.2 → NP_080633.2  RIB43A-like with coiled-coils protein 2

      See identical proteins and their annotated locations for NP_080633.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the protein coding variant.
      Source sequence(s)
      AK016311, BY716712
      Consensus CDS
      CCDS49689.1
      UniProtKB/Swiss-Prot
      G3X8W0, Q9D4Q1
      Related
      ENSMUSP00000023067.3, ENSMUST00000023067.4
      Conserved Domains (1) summary
      pfam05914
      Location:3 → 377
      RIB43A

    RNA

    1. NR_152195.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) contains an alternate internal exon, compared to variant 1. This variant is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AL772308
      Related
      ENSMUST00000229238.2

    2. NR_164346.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL772308

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      85016261..85028771
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036159551.1 → XP_036015444.1  RIB43A-like with coiled-coils protein 2 isoform X1

      Conserved Domains (1) summary
      pfam05914
      Location:6 → 204
      RIB43A

    2. XM_036159552.1 → XP_036015445.1  RIB43A-like with coiled-coils protein 2 isoform X1

      Conserved Domains (1) summary
      pfam05914
      Location:6 → 204
      RIB43A

    3. XM_036159553.1 → XP_036015446.1  RIB43A-like with coiled-coils protein 2 isoform X1

      Conserved Domains (1) summary
      pfam05914
      Location:6 → 204
      RIB43A

    RNA

    1. XR_004938865.1 RNA Sequence

    2. XR_004938866.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9D4Q1.3 GenPept UniProtKB/Swiss-Prot:Q9D4Q1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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