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    Nudt22 nudix hydrolase 22 [ Mus musculus (house mouse) ]

    Gene ID: 68323, updated on 21-Apr-2024

    Summary

    Official Symbol
    Nudt22provided by MGI
    Official Full Name
    nudix hydrolase 22provided by MGI
    Primary source
    MGI:MGI:1915573
    See related
    Ensembl:ENSMUSG00000037349 AllianceGenome:MGI:1915573
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    0610006K04Rik
    Summary
    Predicted to enable GDP-mannose hydrolase activity; UDP-sugar diphosphatase activity; and metal ion binding activity. Predicted to be located in nucleoplasm. Orthologous to human NUDT22 (nudix hydrolase 22). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in adrenal adult (RPKM 56.2), colon adult (RPKM 38.4) and 28 other tissues See more
    Orthologs
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    Genomic context

    Location:
    19 A; 19 5.13 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 19 NC_000085.7 (6970387..6973471, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 19 NC_000085.6 (6993019..6996103, complement)

    Chromosome 19 - NC_000085.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 54053 Neighboring gene vascular endothelial growth factor B Neighboring gene STARR-positive B cell enhancer ABC_E1971 Neighboring gene DnaJ heat shock protein family (Hsp40) member C4 Neighboring gene tRNA phosphotransferase 1 Neighboring gene fermitin family member 3 Neighboring gene CapStarr-seq enhancer MGSCv37_chr19:7092729-7092882 Neighboring gene predicted gene, 54052 Neighboring gene stress-induced phosphoprotein 1 Neighboring gene STARR-seq mESC enhancer starr_45447

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (1) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables GDP-mannose hydrolase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables UDP-sugar diphosphatase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables metal ion binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    uridine diphosphate glucose pyrophosphatase NUDT22
    Names
    UDPG pyrophosphatase
    UGPPase
    nucleoside diphosphate-linked moiety X motif 22
    nudix (nucleoside diphosphate linked moiety X)-type motif 22
    nudix motif 22
    NP_080951.1
    XP_030106926.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026675.2NP_080951.1  uridine diphosphate glucose pyrophosphatase NUDT22

      See identical proteins and their annotated locations for NP_080951.1

      Status: VALIDATED

      Source sequence(s)
      AK002252
      Consensus CDS
      CCDS29517.1
      UniProtKB/Swiss-Prot
      Q8VCI4, Q9DD16
      Related
      ENSMUSP00000041419.3, ENSMUST00000041686.10

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000085.7 Reference GRCm39 C57BL/6J

      Range
      6970387..6973471 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030251066.1XP_030106926.1  uridine diphosphate glucose pyrophosphatase NUDT22 isoform X1