Urm1 ubiquitin related modifier 1 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Urm1provided by MGI
Official Full Name: ubiquitin related modifier 1provided by MGI
Primary source: MGI:MGI:1915455
See related: Ensembl:ENSMUSG00000069020 AllianceGenome:MGI:1915455
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: 2900073H19Rik
Summary: Predicted to enable protein tag and sulfur carrier activity. Predicted to be involved in protein urmylation; tRNA thio-modification; and tRNA wobble uridine modification. Predicted to act upstream of or within tRNA processing. Predicted to be located in cytoplasm. Predicted to be active in nucleus. Is expressed in mandible; nervous system; and neural retina. Orthologous to human URM1 (ubiquitin related modifier 1). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in limb E14.5 (RPKM 14.2), cerebellum adult (RPKM 13.3) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 2 B; 2 20.67 cM

Exon count:: 5

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	2	NC_000068.8 (29717401..29735008)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	2	NC_000068.7 (29827389..29844996)

Chromosome 2 - NC_000068.8 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

The emerging roles of ubiquitin-like protein Urm1 in eukaryotes.
Title: The emerging roles of ubiquitin-like protein Urm1 in eukaryotes.
Structural model of the Urm1 protein reveals a secondary structure fold similar to MoaD proteins and ubiquitin.
Title: Three-dimensional structure of the AAH26994.1 protein from Mus musculus, a putative eukaryotic Urm1.

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Markers

Urm1 (e-PCR), detects polymorphism
- UniSTS:527600

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables protein tag activity	IBA Inferred from Biological aspect of Ancestor more info
enables sulfur carrier activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in protein urmylation	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within tRNA processing	IEA Inferred from Electronic Annotation more info
involved_in tRNA thio-modification	ISO Inferred from Sequence Orthology more info
involved_in tRNA wobble uridine modification	ISO Inferred from Sequence Orthology more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
is_active_in nucleus	IBA Inferred from Biological aspect of Ancestor more info

General protein information

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Preferred Names: ubiquitin-related modifier 1

Names: ubiquitin-related modifier 1 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.