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    P3r3urf Pik3r3 upstream reading frame [ Mus musculus (house mouse) ]

    Gene ID: 67323, updated on 16-Mar-2024

    Summary

    Official Symbol
    P3r3urfprovided by MGI
    Official Full Name
    Pik3r3 upstream reading frameprovided by MGI
    Primary source
    MGI:MGI:1914573
    See related
    Ensembl:ENSMUSG00000078593 AllianceGenome:MGI:1914573
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1700042G07Rik
    Summary
    Predicted to enable 1-phosphatidylinositol-3-kinase regulator activity and phosphotyrosine residue binding activity. Predicted to be involved in phosphatidylinositol phosphate biosynthetic process. Predicted to be part of phosphatidylinositol 3-kinase complex. Human ortholog(s) of this gene implicated in colon adenocarcinoma. Orthologous to several human genes including PIK3R3 (phosphoinositide-3-kinase regulatory subunit 3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward testis adult (RPKM 179.1) See more
    Orthologs
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    Genomic context

    Location:
    4 D1; 4 53.1 cM
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (116030569..116031494)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (116173372..116174297)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase Neighboring gene tetraspanin 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr4:115849369-115849478 Neighboring gene STARR-seq mESC enhancer starr_11134 Neighboring gene LLP homolog, pseudogene 1 Neighboring gene STARR-seq mESC enhancer starr_11135 Neighboring gene STARR-positive B cell enhancer ABC_E838 Neighboring gene phosphoinositide-3-kinase regulatory subunit 3 Neighboring gene BRCA1 associated RING domain 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 1-phosphatidylinositol-3-kinase regulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in phosphatidylinositol phosphate biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of phosphatidylinositol 3-kinase complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    PIK3R3 upstream open reading frame protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001099295.2NP_001092765.1  PIK3R3 upstream open reading frame protein

      See identical proteins and their annotated locations for NP_001092765.1

      Status: VALIDATED

      Source sequence(s)
      AK006685, BU946248
      Consensus CDS
      CCDS51276.1
      UniProtKB/Swiss-Prot
      B1AUF7
      Related
      ENSMUSP00000102101.3, ENSMUST00000106492.3

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      116030569..116031494
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)