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    Med29 mediator complex subunit 29 [ Mus musculus (house mouse) ]

    Gene ID: 67224, updated on 5-Mar-2024

    Summary

    Official Symbol
    Med29provided by MGI
    Official Full Name
    mediator complex subunit 29provided by MGI
    Primary source
    MGI:MGI:1914474
    See related
    Ensembl:ENSMUSG00000003444 AllianceGenome:MGI:1914474
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ixl; 2810405O22Rik
    Summary
    Predicted to enable transcription coregulator activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of mediator complex. Orthologous to human MED29 (mediator complex subunit 29). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in testis adult (RPKM 28.8), adrenal adult (RPKM 23.3) and 28 other tissues See more
    Orthologs
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    Genomic context

    Location:
    7 A3; 7 16.72 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (28084667..28092126, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (28385247..28392690, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene pleckstrin homology domain containing, family G (with RhoGef domain) member 2 Neighboring gene STARR-positive B cell enhancer ABC_E1728 Neighboring gene STARR-seq mESC enhancer starr_18413 Neighboring gene nuclear encoded tRNA isoleucine 16 (anticodon TAT) Neighboring gene STARR-positive B cell enhancer ABC_E2821 Neighboring gene STARR-seq mESC enhancer starr_18414 Neighboring gene Paf1, RNA polymerase II complex component Neighboring gene zinc finger protein 36 Neighboring gene STARR-positive B cell enhancer ABC_E289 Neighboring gene sterile alpha motif domain containing 4B Neighboring gene STARR-positive B cell enhancer ABC_E240 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:29225831-29226014 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:29231461-29231644 Neighboring gene STARR-seq mESC enhancer starr_18417 Neighboring gene glia maturation factor, gamma

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables transcription coregulator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables transcription factor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of core mediator complex ISO
    Inferred from Sequence Orthology
    more info
     
    part_of mediator complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of mediator complex ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    mediator of RNA polymerase II transcription subunit 29
    Names
    intersex-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026042.4NP_080318.2  mediator of RNA polymerase II transcription subunit 29

      See identical proteins and their annotated locations for NP_080318.2

      Status: VALIDATED

      Source sequence(s)
      AC149606
      Consensus CDS
      CCDS21042.1
      UniProtKB/Swiss-Prot
      Q9DB91
      Related
      ENSMUSP00000003536.9, ENSMUST00000003536.9
      Conserved Domains (1) summary
      pfam11568
      Location:52186
      Med29; Mediator complex subunit 29

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      28084667..28092126 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)