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    Eid3 EP300 interacting inhibitor of differentiation 3 [ Mus musculus (house mouse) ]

    Gene ID: 66341, updated on 11-Apr-2024

    Summary

    Official Symbol
    Eid3provided by MGI
    Official Full Name
    EP300 interacting inhibitor of differentiation 3provided by MGI
    Primary source
    MGI:MGI:1913591
    See related
    Ensembl:ENSMUSG00000109864 AllianceGenome:MGI:1913591
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    NS4EB; 1700027M21Rik
    Summary
    Predicted to be involved in DNA repair. Predicted to act upstream of or within DNA recombination and cellular response to DNA damage stimulus. Predicted to be located in nucleolus and nucleoplasm. Predicted to be part of Smc5-Smc6 complex. Predicted to be active in nucleus. Orthologous to human EID3 (EP300 interacting inhibitor of differentiation 3). [provided by Alliance of Genome Resources, Apr 2022]
    Orthologs
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    Genomic context

    Location:
    10 C1; 10 40.66 cM
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 10 NC_000076.7 (82702460..82703764)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 10 NC_000076.6 (82866626..82867930)

    Chromosome 10 - NC_000076.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700028I16 gene Neighboring gene STARR-seq mESC enhancer starr_27376 Neighboring gene STARR-positive B cell enhancer ABC_E9798 Neighboring gene STARR-seq mESC enhancer starr_27377 Neighboring gene thioredoxin reductase 1 Neighboring gene predicted gene, 38560 Neighboring gene STARR-seq mESC enhancer starr_27378 Neighboring gene STARR-positive B cell enhancer ABC_E3903 Neighboring gene STARR-positive B cell enhancer ABC_E5161 Neighboring gene STARR-positive B cell enhancer ABC_E10633 Neighboring gene predicted gene, 33781 Neighboring gene predicted gene 4799

    Genomic regions, transcripts, and products

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Clone Names

    • MGC118226

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    acts_upstream_of_or_within DNA damage response IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within DNA recombination IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in DNA repair IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    part_of Smc5-Smc6 complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of Smc5-Smc6 complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in chromosome IEA
    Inferred from Electronic Annotation
    more info
     
    located_in chromosome, telomeric region IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    EP300-interacting inhibitor of differentiation 3
    Names
    EID-1-like inhibitor of differentiation 3
    non-SMC element 4 homolog B
    non-structural maintenance of chromosomes element 4 homolog B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_025499.2NP_079775.2  EP300-interacting inhibitor of differentiation 3

      See identical proteins and their annotated locations for NP_079775.2

      Status: VALIDATED

      Source sequence(s)
      BC099545, CJ046810
      Consensus CDS
      CCDS83739.1
      UniProtKB/Swiss-Prot
      Q3TTL4, Q3V124, Q4KL03, Q8CF34, Q9CVN8
      Related
      ENSMUSP00000147261.2, ENSMUST00000211623.2
      Conserved Domains (2) summary
      pfam08743
      Location:283371
      Nse4_C; Nse4 C-terminal
      pfam15412
      Location:132178
      Nse4-Nse3_bdg; Binding domain of Nse4/EID3 to Nse3-MAGE

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000076.7 Reference GRCm39 C57BL/6J

      Range
      82702460..82703764
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)