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    Fam184b family with sequence similarity 184, member B [ Mus musculus (house mouse) ]

    Gene ID: 58227, updated on 21-Apr-2024

    Summary

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    Official Symbol
    Fam184bprovided by MGI
    Official Full Name
    family with sequence similarity 184, member Bprovided by MGI
    Primary source
    MGI:MGI:2442958
    See related
    Ensembl:ENSMUSG00000015879 AllianceGenome:MGI:2442958
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9630031F12Rik
    Summary
    Is expressed in several structures, including gut; male reproductive gland or organ; nervous system; rib; and sensory organ. Orthologous to human FAM184B (family with sequence similarity 184 member B). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in frontal lobe adult (RPKM 1.7), cerebellum adult (RPKM 1.6) and 11 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    5 B3; 5 25.04 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (45687047..45796843, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (45529705..45639501, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E6329 Neighboring gene STARR-seq mESC enhancer starr_12997 Neighboring gene leucine aminopeptidase 3 Neighboring gene mediator complex subunit 28 Neighboring gene STARR-seq mESC enhancer starr_13000 Neighboring gene STARR-seq mESC enhancer starr_13001 Neighboring gene STARR-seq mESC enhancer starr_13002 Neighboring gene STARR-seq mESC enhancer starr_13003 Neighboring gene STARR-seq mESC enhancer starr_13004 Neighboring gene RIKEN cDNA 9630001P10 gene Neighboring gene STARR-seq mESC enhancer starr_13005 Neighboring gene RIKEN cDNA 1600023N17 gene Neighboring gene STARR-positive B cell enhancer ABC_E1300 Neighboring gene DDB1 and CUL4 associated factor 16 pseudogene

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A gene-targeting approach for functional characterization of KIAA genes encoding extremely large proteins. Nakayama M, et al. FASEB J, 2006 Aug. PMID 16807365
    2. An expression profile analysis of ES cell-derived definitive endodermal cells and Pdx1-expressing cells. Ogaki S, et al. BMC Dev Biol, 2011 Mar 1. PMID 21362171, Free PMC Article
    3. Targeting a complex transcriptome: the construction of the mouse full-length cDNA encyclopedia. Carninci P, et al. Genome Res, 2003 Jun. PMID 12819125, Free PMC Article
    4. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
    5. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (5)  1 citation
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • KIAA1276

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM184B

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_021416.3 → NP_067391.3  protein FAM184B

      See identical proteins and their annotated locations for NP_067391.3

      Status: VALIDATED

      Source sequence(s)
      AB093291, BC056379, BY794536, CF539972
      Consensus CDS
      CCDS19276.1
      UniProtKB/Swiss-Prot
      Q0KK51, Q0KK56, Q76KB4, Q7TNB6, Q9JJG2
      Related
      ENSMUSP00000016023.8, ENSMUST00000016023.9
      Conserved Domains (3) summary
      COG1196
      Location:95 → 813
      Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
      pfam15665
      Location:50 → 239
      FAM184; Family with sequence similarity 184, A and B
      cl19219
      Location:381 → 481
      DUF342; Protein of unknown function (DUF342)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      45687047..45796843 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q0KK56.1 GenPept UniProtKB/Swiss-Prot:Q0KK56

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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