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    Copz2 coatomer protein complex, subunit zeta 2 [ Mus musculus (house mouse) ]

    Gene ID: 56358, updated on 11-Apr-2024

    Summary

    Official Symbol
    Copz2provided by MGI
    Official Full Name
    coatomer protein complex, subunit zeta 2provided by MGI
    Primary source
    MGI:MGI:1929008
    See related
    Ensembl:ENSMUSG00000018672 AllianceGenome:MGI:1929008
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    zeta2-COP; 1110012D12Rik
    Summary
    Predicted to be involved in intra-Golgi vesicle-mediated transport; intracellular protein transport; and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to act upstream of or within protein transport and vesicle-mediated transport. Predicted to be located in COPI-coated vesicle. Predicted to be part of COPI vesicle coat. Orthologous to human COPZ2 (COPI coat complex subunit zeta 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in bladder adult (RPKM 34.8), limb E14.5 (RPKM 33.8) and 28 other tissues See more
    Orthologs
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    Genomic context

    Location:
    11 D; 11 60.13 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (96740702..96752029)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (96849876..96861203)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene chromobox 1 Neighboring gene ubiquitin A-52 residue ribosomal protein fusion product 1 pseudogene Neighboring gene STARR-seq mESC enhancer starr_30564 Neighboring gene STARR-seq mESC enhancer starr_30565 Neighboring gene STARR-positive B cell enhancer ABC_E9144 Neighboring gene nuclear factor, erythroid derived 2,-like 1 Neighboring gene STARR-positive B cell enhancer ABC_E9371 Neighboring gene STARR-positive B cell enhancer ABC_E201 Neighboring gene microRNA 152 Neighboring gene STARR-positive B cell enhancer ABC_E2366 Neighboring gene predicted gene 11523 Neighboring gene VISTA enhancer mm1299 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene VISTA enhancers mm876 and mm999 Neighboring gene STARR-seq mESC enhancer starr_30571 Neighboring gene predicted gene, 38961 Neighboring gene VISTA enhancer mm1675

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in intra-Golgi vesicle-mediated transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intracellular protein transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within vesicle-mediated transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    part_of COPI vesicle coat IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of COPI vesicle coat ISO
    Inferred from Sequence Orthology
    more info
     
    located_in COPI-coated vesicle ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in Golgi apparatus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    coatomer subunit zeta-2
    Names
    nonclathrin coat protein zeta2-COP
    zeta-2 COP
    zeta-2-coat protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019877.2NP_063930.1  coatomer subunit zeta-2

      See identical proteins and their annotated locations for NP_063930.1

      Status: VALIDATED

      Source sequence(s)
      AB040137
      Consensus CDS
      CCDS25305.1
      UniProtKB/Swiss-Prot
      A2A6D6, Q9JHH9
      UniProtKB/TrEMBL
      Q9CTG7
      Related
      ENSMUSP00000018816.8, ENSMUST00000018816.14
      Conserved Domains (1) summary
      cl02092
      Location:40174
      Clat_adaptor_s; Clathrin adaptor complex small chain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      96740702..96752029
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)