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    Mrpl19 mitochondrial ribosomal protein L19 [ Mus musculus (house mouse) ]

    Gene ID: 56284, updated on 5-Mar-2024

    Summary

    Official Symbol
    Mrpl19provided by MGI
    Official Full Name
    mitochondrial ribosomal protein L19provided by MGI
    Primary source
    MGI:MGI:1926274
    See related
    Ensembl:ENSMUSG00000030045 AllianceGenome:MGI:1926274
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    RLX1; Rpml15; MRP-L15; D6Ertd157e; 9030416F12Rik; 9130412E02Rik
    Summary
    Predicted to be a structural constituent of ribosome. Predicted to act upstream of or within translation. Located in mitochondrion. Is expressed in several structures, including early conceptus; gonad; heart; liver; and metanephros. Orthologous to human MRPL19 (mitochondrial ribosomal protein L19). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 6.3), CNS E18 (RPKM 4.6) and 28 other tissues See more
    Orthologs
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    Genomic context

    Location:
    6 C3; 6 35.81 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 6 NC_000072.7 (81934807..81942930, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 6 NC_000072.6 (81957826..81965949, complement)

    Chromosome 6 - NC_000072.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 1700009C05 gene Neighboring gene microRNA 468 Neighboring gene GC-rich sequence DNA binding factor 2 Neighboring gene STARR-positive B cell enhancer ABC_E9274 Neighboring gene STARR-seq mESC enhancer starr_16423 Neighboring gene predicted gene, 38842 Neighboring gene predicted gene, 20383

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural constituent of ribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables structural constituent of ribosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in mitochondrial translation NAS
    Non-traceable Author Statement
    more info
    PubMed 
    acts_upstream_of_or_within translation ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in mitochondrial inner membrane NAS
    Non-traceable Author Statement
    more info
    PubMed 
    part_of mitochondrial large ribosomal subunit IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of mitochondrial large ribosomal subunit ISO
    Inferred from Sequence Orthology
    more info
     
    part_of mitochondrial large ribosomal subunit NAS
    Non-traceable Author Statement
    more info
    PubMed 
    located_in mitochondrial ribosome ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    located_in mitochondrion HDA PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     
    located_in ribosome IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    large ribosomal subunit protein bL19m
    Names
    39S ribosomal protein L19, mitochondrial
    L19mt
    MRP-L19
    ribosomal protein, mitochondrial, L15

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_026490.2NP_080766.1  large ribosomal subunit protein bL19m

      See identical proteins and their annotated locations for NP_080766.1

      Status: VALIDATED

      Source sequence(s)
      AC129024, AK018508
      Consensus CDS
      CCDS39523.1
      UniProtKB/Swiss-Prot
      Q543I0, Q8R1R0, Q9D338
      UniProtKB/TrEMBL
      Q6P8U3
      Related
      ENSMUSP00000032124.9, ENSMUST00000032124.9
      Conserved Domains (1) summary
      cl00406
      Location:108192
      Ribosomal_L19; Ribosomal protein L19

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000072.7 Reference GRCm39 C57BL/6J

      Range
      81934807..81942930 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)