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    Rnf24 ring finger protein 24 [ Mus musculus (house mouse) ]

    Gene ID: 51902, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Rnf24provided by MGI
    Official Full Name
    ring finger protein 24provided by MGI
    Primary source
    MGI:MGI:1261771
    See related
    Ensembl:ENSMUSG00000048911 AllianceGenome:MGI:1261771
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    D2Ertd504e; 2810473M14Rik; 4930505A13Rik
    Summary
    Predicted to enable ubiquitin protein ligase activity. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in Golgi apparatus. Is expressed in early conceptus and genitourinary system. Orthologous to human RNF24 (ring finger protein 24). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in testis adult (RPKM 10.0), whole brain E14.5 (RPKM 9.9) and 25 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    2 F1; 2 63.32 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (131139984..131194766, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (131298488..131352892, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E4499 Neighboring gene mitochondrial antiviral signaling protein Neighboring gene STARR-positive B cell enhancer ABC_E5984 Neighboring gene STARR-seq mESC enhancer starr_05706 Neighboring gene STARR-seq mESC enhancer starr_05707 Neighboring gene pantothenate kinase 2 Neighboring gene microRNA 103-2 Neighboring gene small nuclear ribonucleoprotein E, pseudogene Neighboring gene predicted gene, 30590 Neighboring gene STARR-seq mESC enhancer starr_05709 Neighboring gene aldo-keto reductase family 1 member A1-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. ELAC2 Functions as a Key Gene in the Early Development of Placental Formation Based on WGCNA. Liang J, et al. Cells, 2023 Feb 14. PMID 36831280, Free PMC Article
    2. Identification of novel oocyte and granulosa cell markers. Malcuit C, et al. Gene Expr Patterns, 2009 Sep. PMID 19539053
    3. Characterization of an exchangeable gene trap using pU-17 carrying a stop codon-beta geo cassette. Taniwaki T, et al. Dev Growth Differ, 2005 Apr. PMID 15840001
    4. Exchangeable gene trap using the Cre/mutated lox system. Araki K, et al. Cell Mol Biol (Noisy-le-grand), 1999 Jul. PMID 10512203
    5. BioID screening of biotinylation sites using the avidin-like protein Tamavidin 2-REV identifies global interactors of stimulator of interferon genes (STING). Motani K, et al. J Biol Chem, 2020 Aug 7. PMID 32554809, Free PMC Article

    See all (24) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables zinc ion binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    RING finger protein 24

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178607.5 → NP_848722.1  RING finger protein 24

      See identical proteins and their annotated locations for NP_848722.1

      Status: VALIDATED

      Source sequence(s)
      AL808128
      Consensus CDS
      CCDS16762.1
      UniProtKB/Swiss-Prot
      Q8BGI1
      UniProtKB/TrEMBL
      Q4VA59
      Related
      ENSMUSP00000058630.5, ENSMUST00000059372.11
      Conserved Domains (1) summary
      cd16469
      Location:76 → 122
      RING-H2_RNF24_like; RING finger, H2 subclass, found in RING finger proteins RNF24, RNF122, and similar proteins

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      131139984..131194766 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BGI1.1 GenPept UniProtKB/Swiss-Prot:Q8BGI1

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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