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    Ubfd1 ubiquitin family domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 28018, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Ubfd1provided by MGI
    Official Full Name
    ubiquitin family domain containing 1provided by MGI
    Primary source
    MGI:MGI:107301
    See related
    Ensembl:ENSMUSG00000030870 AllianceGenome:MGI:107301
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Ubph; D7Wsu105e; D7Wsu128e
    Summary
    Is expressed in embryo and extraembryonic component. Orthologous to human UBFD1 (ubiquitin family domain containing 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 24.0), CNS E18 (RPKM 23.9) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    7 F2; 7 65.35 cM
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (121666318..121681422)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (122067095..122082199)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene component of oligomeric golgi complex 7 Neighboring gene STARR-seq mESC enhancer starr_20069 Neighboring gene golgi associated, gamma adaptin ear containing, ARF binding protein 2 Neighboring gene STARR-positive B cell enhancer ABC_E10471 Neighboring gene glutamyl-tRNA synthetase 2, mitochondrial Neighboring gene STARR-positive B cell enhancer ABC_E3748 Neighboring gene NADH:ubiquinone oxidoreductase subunit AB1 Neighboring gene partner and localizer of BRCA2 Neighboring gene 60S ribosomal protein L27-like

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy. McLelland GL, et al. Elife, 2018 Apr 20. PMID 29676259, Free PMC Article
    2. Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Ko MS, et al. Hum Mol Genet, 1998 Nov. PMID 9811942
    3. An Interaction Landscape of Ubiquitin Signaling. Zhang X, et al. Mol Cell, 2017 Mar 2. PMID 28190767
    4. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    5. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, et al. Development, 2000 Apr. PMID 10725249

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    ubiquitin domain-containing protein UBFD1
    Names
    ubiquitin-binding protein homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_138589.2 → NP_613055.2  ubiquitin domain-containing protein UBFD1

      See identical proteins and their annotated locations for NP_613055.2

      Status: PROVISIONAL

      Source sequence(s)
      AC124379, AK077395
      Consensus CDS
      CCDS21808.1
      UniProtKB/Swiss-Prot
      Q78JW9
      Related
      ENSMUSP00000033158.5, ENSMUST00000033158.6
      Conserved Domains (1) summary
      pfam00240
      Location:151 → 215
      ubiquitin; Ubiquitin family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      121666318..121681422
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006507914.4 → XP_006507977.3  ubiquitin domain-containing protein UBFD1 isoform X2

      Conserved Domains (1) summary
      cd17047
      Location:145 → 214
      Ubl_UBFD1; ubiquitin-like (Ubl) domain found in ubiquitin domain-containing protein UBFD1 and similar proteins

    2. XM_006507913.5 → XP_006507976.3  ubiquitin domain-containing protein UBFD1 isoform X1

      Conserved Domains (1) summary
      cd17047
      Location:145 → 214
      Ubl_UBFD1; ubiquitin-like (Ubl) domain found in ubiquitin domain-containing protein UBFD1 and similar proteins

    3. XM_006507915.5 → XP_006507978.3  ubiquitin domain-containing protein UBFD1 isoform X3

      Conserved Domains (1) summary
      cd17047
      Location:145 → 214
      Ubl_UBFD1; ubiquitin-like (Ubl) domain found in ubiquitin domain-containing protein UBFD1 and similar proteins
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q78JW9.2 GenPept UniProtKB/Swiss-Prot:Q78JW9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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