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    Srp9 signal recognition particle 9 [ Mus musculus (house mouse) ]

    Gene ID: 27058, updated on 11-Apr-2024

    Summary

    Official Symbol
    Srp9provided by MGI
    Official Full Name
    signal recognition particle 9provided by MGI
    Primary source
    MGI:MGI:1350930
    See related
    Ensembl:ENSMUSG00000026511 AllianceGenome:MGI:1350930
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    9kDa
    Summary
    Predicted to enable 7S RNA binding activity. Predicted to be involved in SRP-dependent cotranslational protein targeting to membrane. Predicted to be located in cytoplasm. Predicted to be part of signal recognition particle, endoplasmic reticulum targeting. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Orthologous to human SRP9 (signal recognition particle 9). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in placenta adult (RPKM 43.4), testis adult (RPKM 34.4) and 28 other tissues See more
    Orthologs
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    Genomic context

    Location:
    1 H5; 1 84.93 cM
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (181952302..181959980)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (182124737..182132415)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_03262 Neighboring gene nuclear encoded tRNA serine 1 (anticodon GCT) Neighboring gene predicted gene, 39719 Neighboring gene predicted gene, 33725 Neighboring gene STARR-positive B cell enhancer ABC_E7783 Neighboring gene STARR-positive B cell enhancer ABC_E11700 Neighboring gene STARR-positive B cell enhancer ABC_E3346 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene STARR-seq mESC enhancer starr_03268 Neighboring gene STARR-seq mESC enhancer starr_03269 Neighboring gene vomeronasal 1 receptor 1 Neighboring gene STARR-seq mESC enhancer starr_03270 Neighboring gene STARR-seq mESC enhancer starr_03273 Neighboring gene STARR-seq mESC enhancer starr_03274 Neighboring gene STARR-seq mESC enhancer starr_03276 Neighboring gene predicted gene, 33887

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 7S RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in SRP-dependent cotranslational protein targeting to membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in negative regulation of translational elongation IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    part_of ribonucleoprotein complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of signal recognition particle IEA
    Inferred from Electronic Annotation
    more info
     
    part_of signal recognition particle, endoplasmic reticulum targeting IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    signal recognition particle 9 kDa protein
    NP_036188.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012058.3NP_036188.1  signal recognition particle 9 kDa protein

      See identical proteins and their annotated locations for NP_036188.1

      Status: VALIDATED

      Source sequence(s)
      AK051208, AK146882, CJ047061
      Consensus CDS
      CCDS35812.1
      UniProtKB/Swiss-Prot
      P49962, Q9D085
      UniProtKB/TrEMBL
      Q3UIK3, Q5EAT0
      Related
      ENSMUSP00000027792.6, ENSMUST00000027792.6
      Conserved Domains (1) summary
      pfam05486
      Location:473
      SRP9-21; Signal recognition particle 9 kDa protein (SRP9)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      181952302..181959980
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)