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    Dpy19l3 dpy-19 like C-mannosyltransferase 3 [ Mus musculus (house mouse) ]

    Gene ID: 233115, updated on 20-Apr-2024

    Summary

    Official Symbol
    Dpy19l3provided by MGI
    Official Full Name
    dpy-19 like C-mannosyltransferase 3provided by MGI
    Primary source
    MGI:MGI:2443952
    See related
    Ensembl:ENSMUSG00000043671 AllianceGenome:MGI:2443952
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    6030410G08; 9330164H19Rik
    Summary
    Predicted to enable mannosyltransferase activity. Predicted to be involved in protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in nuclear inner membrane. Is expressed in cerebral cortex. Orthologous to human DPY19L3 (dpy-19 like C-mannosyltransferase 3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 5.0), CNS E14 (RPKM 4.9) and 27 other tissues See more
    Orthologs
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    Genomic context

    Location:
    7 B2; 7 21.37 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (35384925..35453879, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (35685500..35754460, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E8165 Neighboring gene programmed cell death 5 Neighboring gene predicted gene, 42379 Neighboring gene STARR-seq mESC enhancer starr_18641 Neighboring gene zinc finger protein 507 Neighboring gene RIKEN cDNA E130304I02 gene Neighboring gene predicted gene, 36234

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables glycosyltransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables mannosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables mannosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables mannosyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in protein C-linked glycosylation via 2'-alpha-mannosyl-L-tryptophan IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nuclear inner membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    protein C-mannosyl-transferase DPY19L3; probable C-mannosyltransferase DPY19L3
    Names
    dpy-19-like 3
    dpy-19-like protein 3
    protein dpy-19 homolog 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_178704.3NP_848819.2  protein C-mannosyl-transferase DPY19L3

      See identical proteins and their annotated locations for NP_848819.2

      Status: VALIDATED

      Source sequence(s)
      AC166160, AK034217, AK045758
      Consensus CDS
      CCDS21155.1
      UniProtKB/Swiss-Prot
      Q6PB46, Q71B07, Q80W29, Q8BLA9, Q8BZL3, Q8BZW5
      Related
      ENSMUSP00000054747.9, ENSMUST00000051377.15
      Conserved Domains (1) summary
      pfam10034
      Location:56711
      Dpy19; Q-cell neuroblast polarization

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      35384925..35453879 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006539906.2XP_006539969.1  probable C-mannosyltransferase DPY19L3 isoform X1

      Conserved Domains (1) summary
      pfam10034
      Location:1449
      Dpy19; Q-cell neuroblast polarisation