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    Zfp790 zinc finger protein 790 [ Mus musculus (house mouse) ]

    Gene ID: 233056, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Zfp790provided by MGI
    Official Full Name
    zinc finger protein 790provided by MGI
    Primary source
    MGI:MGI:1923431
    See related
    Ensembl:ENSMUSG00000011427 AllianceGenome:MGI:1923431
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    6330581L23Rik
    Summary
    Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II. Is expressed in several structures, including 1st branchial arch; early conceptus; eye; maxillary process; and oocyte. Orthologous to human ZNF790 (zinc finger protein 790). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 2.5), CNS E14 (RPKM 2.4) and 28 other tissues See more
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    Genomic context

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    Location:
    7 B1; 7 17.26 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (29510862..29531467)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (29811437..29832042)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_18488 Neighboring gene zinc finger protein 30 Neighboring gene predicted gene 6579 Neighboring gene STARR-seq mESC enhancer starr_18490 Neighboring gene STARR-seq mESC enhancer starr_18491 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:30601028-30601137 Neighboring gene zinc finger protein 940 Neighboring gene STARR-positive B cell enhancer ABC_E8836 Neighboring gene STARR-positive B cell enhancer ABC_E10434 Neighboring gene zinc finger protein 420

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta. Thuret S, et al. Mol Cell Neurosci, 2004 Mar. PMID 15033168
    2. Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst. Guo G, et al. Dev Cell, 2010 Apr 20. PMID 20412781
    3. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
    4. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518
    5. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    General gene information

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    Homology

    Clone Names

    • MGC6654

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    zinc finger protein 790

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001145880.1 → NP_001139352.1  zinc finger protein 790

      See identical proteins and their annotated locations for NP_001139352.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK018258, AK030519, BC046774, BG081821, BQ443561, CJ228115
      Consensus CDS
      CCDS52174.1
      UniProtKB/TrEMBL
      Q80ZX2, Q91VW8
      Related
      ENSMUSP00000136932.2, ENSMUST00000178162.3
      Conserved Domains (4) summary
      smart00349
      Location:5 → 61
      KRAB; krueppel associated box
      COG5048
      Location:224 → 686
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:282 → 302
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:682 → 707
      zf-H2C2_2; Zinc-finger double domain

    2. NM_146185.2 → NP_666297.2  zinc finger protein 790

      See identical proteins and their annotated locations for NP_666297.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AK018258, AK030519, BC046774, BG081821, CJ228115
      Consensus CDS
      CCDS52174.1
      UniProtKB/TrEMBL
      Q80ZX2, Q91VW8
      Related
      ENSMUSP00000032796.7, ENSMUST00000032796.14
      Conserved Domains (4) summary
      smart00349
      Location:5 → 61
      KRAB; krueppel associated box
      COG5048
      Location:224 → 686
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:282 → 302
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:682 → 707
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      29510862..29531467
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011250532.3 → XP_011248834.1  zinc finger protein 790 isoform X1

      See identical proteins and their annotated locations for XP_011248834.1

      UniProtKB/TrEMBL
      Q80ZX2, Q91VW8
      Conserved Domains (4) summary
      smart00349
      Location:5 → 61
      KRAB; krueppel associated box
      COG5048
      Location:224 → 686
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:282 → 302
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:682 → 707
      zf-H2C2_2; Zinc-finger double domain

    2. XM_036152951.1 → XP_036008844.1  zinc finger protein 790 isoform X1

      UniProtKB/TrEMBL
      Q80ZX2, Q91VW8
      Conserved Domains (4) summary
      smart00349
      Location:5 → 61
      KRAB; krueppel associated box
      COG5048
      Location:224 → 686
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:282 → 302
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:682 → 707
      zf-H2C2_2; Zinc-finger double domain

    3. XM_011250533.3 → XP_011248835.1  zinc finger protein 790 isoform X1

      See identical proteins and their annotated locations for XP_011248835.1

      UniProtKB/TrEMBL
      Q80ZX2, Q91VW8
      Conserved Domains (4) summary
      smart00349
      Location:5 → 61
      KRAB; krueppel associated box
      COG5048
      Location:224 → 686
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:282 → 302
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:682 → 707
      zf-H2C2_2; Zinc-finger double domain

    4. XM_011250534.3 → XP_011248836.1  zinc finger protein 790 isoform X1

      See identical proteins and their annotated locations for XP_011248836.1

      UniProtKB/TrEMBL
      Q80ZX2, Q91VW8
      Conserved Domains (4) summary
      smart00349
      Location:5 → 61
      KRAB; krueppel associated box
      COG5048
      Location:224 → 686
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:282 → 302
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam13465
      Location:682 → 707
      zf-H2C2_2; Zinc-finger double domain
    Nucleotide Protein Strain
    Heading Accession and Version

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