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    Tmem125 transmembrane protein 125 [ Mus musculus (house mouse) ]

    Gene ID: 230678, updated on 5-Mar-2024

    Summary

    Official Symbol
    Tmem125provided by MGI
    Official Full Name
    transmembrane protein 125provided by MGI
    Primary source
    MGI:MGI:1923409
    See related
    Ensembl:ENSMUSG00000050854 AllianceGenome:MGI:1923409
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    6330530A05Rik
    Summary
    Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in brain and heart ventricle. Orthologous to human TMEM125 (transmembrane protein 125). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in stomach adult (RPKM 12.6), duodenum adult (RPKM 12.1) and 17 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    Location:
    4 D2.1; 4 54.81 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (118398138..118402110, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (118540941..118544920, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA 2610528J11 gene Neighboring gene ribosomal protein S5 pseudogene Neighboring gene predicted gene, 40237 Neighboring gene cilia and flagella associated protein 57 Neighboring gene predicted gene, 52677

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC48203

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172383.3NP_759015.2  transmembrane protein 125

      See identical proteins and their annotated locations for NP_759015.2

      Status: VALIDATED

      Source sequence(s)
      AK162907, BB653717, BU700816
      Consensus CDS
      CCDS51285.1
      UniProtKB/Swiss-Prot
      A2BI56, Q8BHY6, Q8CHQ6
      Related
      ENSMUSP00000063157.4, ENSMUST00000060214.10
      Conserved Domains (1) summary
      pfam15109
      Location:15125
      TMEM125; TMEM125 protein family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      118398138..118402110 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017320149.3XP_017175638.1  transmembrane protein 125 isoform X1

      UniProtKB/Swiss-Prot
      A2BI56, Q8BHY6, Q8CHQ6
      Conserved Domains (1) summary
      pfam15109
      Location:15125
      TMEM125; TMEM125 protein family
    2. XM_006503013.5XP_006503076.1  transmembrane protein 125 isoform X1

      See identical proteins and their annotated locations for XP_006503076.1

      UniProtKB/Swiss-Prot
      A2BI56, Q8BHY6, Q8CHQ6
      Conserved Domains (1) summary
      pfam15109
      Location:15125
      TMEM125; TMEM125 protein family
    3. XM_011240496.4XP_011238798.1  transmembrane protein 125 isoform X1

      See identical proteins and their annotated locations for XP_011238798.1

      UniProtKB/Swiss-Prot
      A2BI56, Q8BHY6, Q8CHQ6
      Conserved Domains (1) summary
      pfam15109
      Location:15125
      TMEM125; TMEM125 protein family
    4. XM_006503014.4XP_006503077.1  transmembrane protein 125 isoform X1

      See identical proteins and their annotated locations for XP_006503077.1

      UniProtKB/Swiss-Prot
      A2BI56, Q8BHY6, Q8CHQ6
      Conserved Domains (1) summary
      pfam15109
      Location:15125
      TMEM125; TMEM125 protein family