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    Skint10 selection and upkeep of intraepithelial T cells 10 [ Mus musculus (house mouse) ]

    Gene ID: 230613, updated on 8-Feb-2024

    Summary

    Official Symbol
    Skint10provided by MGI
    Official Full Name
    selection and upkeep of intraepithelial T cells 10provided by MGI
    Primary source
    MGI:MGI:2685416
    See related
    Ensembl:ENSMUSG00000048766 AllianceGenome:MGI:2685416
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm570; A030001H23Rik
    Summary
    Predicted to enable signaling receptor binding activity. Predicted to be involved in T cell receptor signaling pathway and regulation of cytokine production. Predicted to be located in membrane. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Is expressed in skin and thymus. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Restricted expression toward thymus adult (RPKM 1.4) See more
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    Genomic context

    Location:
    4 D1; 4 51.53 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (112568027..112632058, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (112710830..112774861, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene selection and upkeep of intraepithelial T cells 2 Neighboring gene STARR-seq mESC enhancer starr_11100 Neighboring gene predicted gene 12817 Neighboring gene TRAF3 interacting protein 2 pseudogene Neighboring gene selection and upkeep of intraepithelial T cells 6 Neighboring gene predicted gene 12816 Neighboring gene multiple inositol polyphosphate histidine phosphatase 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    General gene information

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables signaling receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in T cell receptor signaling pathway IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of cytokine production IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in external side of plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    selection and upkeep of intraepithelial T-cells protein 10
    Names
    skint 10

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_177668.2NP_808336.1  selection and upkeep of intraepithelial T-cells protein 10 precursor

      See identical proteins and their annotated locations for NP_808336.1

      Status: VALIDATED

      Source sequence(s)
      AK037152, AK040044, BB749775
      Consensus CDS
      CCDS38841.1
      UniProtKB/Swiss-Prot
      A7TZG1, A7TZG2, Q8CAZ8
      Related
      ENSMUSP00000058838.4, ENSMUST00000060327.4

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      112568027..112632058 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)