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    Prpf38a PRP38 pre-mRNA processing factor 38 (yeast) domain containing A [ Mus musculus (house mouse) ]

    Gene ID: 230596, updated on 5-Mar-2024

    Summary

    Official Symbol
    Prpf38aprovided by MGI
    Official Full Name
    PRP38 pre-mRNA processing factor 38 (yeast) domain containing Aprovided by MGI
    Primary source
    MGI:MGI:1916962
    See related
    Ensembl:ENSMUSG00000063800 AllianceGenome:MGI:1916962
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    2410002M20Rik
    Summary
    Predicted to be involved in mRNA splicing, via spliceosome. Predicted to act upstream of or within RNA splicing and mRNA processing. Predicted to be located in nucleoplasm. Predicted to be part of U2-type precatalytic spliceosome. Is expressed in lower jaw incisor; submandibular gland primordium; upper jaw incisor; and vibrissa. Orthologous to human PRPF38A (pre-mRNA processing factor 38A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E11.5 (RPKM 34.5), CNS E14 (RPKM 17.5) and 16 other tissues See more
    Orthologs
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    Genomic context

    Location:
    4 C7; 4 50.64 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 4 NC_000070.7 (108422064..108436533, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 4 NC_000070.6 (108564867..108579336, complement)

    Chromosome 4 - NC_000070.7Genomic Context describing neighboring genes Neighboring gene terminal uridylyl transferase 4 Neighboring gene predicted gene, 25827 Neighboring gene predicted gene, 22345 Neighboring gene STARR-positive B cell enhancer ABC_E1036 Neighboring gene origin recognition complex, subunit 1 Neighboring gene predicted gene 12743 Neighboring gene coiled-coil and C2 domain containing 1B Neighboring gene zinc finger, FYVE domain containing 9

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    acts_upstream_of_or_within RNA splicing IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within mRNA processing IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mRNA splicing, via spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of U2-type precatalytic spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    part_of precatalytic spliceosome IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of precatalytic spliceosome ISO
    Inferred from Sequence Orthology
    more info
     
    part_of spliceosomal complex IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    pre-mRNA-splicing factor 38A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172697.3NP_766285.2  pre-mRNA-splicing factor 38A

      See identical proteins and their annotated locations for NP_766285.2

      Status: VALIDATED

      Source sequence(s)
      AV323663, BC024734, BC059875, BY283675
      Consensus CDS
      CCDS18452.1
      UniProtKB/Swiss-Prot
      Q4FK66, Q6PB58, Q8BVY2
      UniProtKB/TrEMBL
      B2RTE3
      Related
      ENSMUSP00000078207.6, ENSMUST00000079213.6
      Conserved Domains (1) summary
      pfam03371
      Location:10172
      PRP38; PRP38 family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000070.7 Reference GRCm39 C57BL/6J

      Range
      108422064..108436533 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)