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    Strip1 striatin interacting protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 229707, updated on 5-Mar-2024

    Summary

    Official Symbol
    Strip1provided by MGI
    Official Full Name
    striatin interacting protein 1provided by MGI
    Primary source
    MGI:MGI:2443884
    See related
    Ensembl:ENSMUSG00000014601 AllianceGenome:MGI:2443884
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Fam40a; 6330569M22Rik; 6530401O14Rik
    Summary
    Enables protein kinase binding activity and small GTPase binding activity. Predicted to be involved in cortical actin cytoskeleton organization and regulation of cell morphogenesis. Predicted to be located in nucleus. Predicted to be active in cytosol. Is expressed in nervous system. Orthologous to human STRIP1 (striatin interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 58.8), CNS E14 (RPKM 55.3) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Strip1 in Genome Data Viewer
    Location:
    3 F2.3; 3 46.83 cM
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (107519848..107539010, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (107612532..107631710, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 36097 Neighboring gene ubiquitin-like 4B Neighboring gene aristaless-like homeobox 3 Neighboring gene CapStarr-seq enhancer MGSCv37_chr3:107434637-107434746 Neighboring gene predicted gene 10961 Neighboring gene S-adenosylhomocysteine hydrolase-like 1 Neighboring gene predicted gene, 52629

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC38111

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein kinase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables small GTPase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cortical actin cytoskeleton organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of cell morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in cytosol IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    striatin-interacting protein 1
    Names
    family with sequence similarity 40, member A
    protein FAM40A

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153563.3NP_705791.2  striatin-interacting protein 1

      See identical proteins and their annotated locations for NP_705791.2

      Status: VALIDATED

      Source sequence(s)
      AC122902
      Consensus CDS
      CCDS51043.1
      UniProtKB/Swiss-Prot
      Q80T92, Q8BZC6, Q8C079, Q8CIF7
      UniProtKB/TrEMBL
      Q3UGC1
      Related
      ENSMUSP00000068587.6, ENSMUST00000064759.7
      Conserved Domains (2) summary
      pfam07923
      Location:66328
      N1221; N1221-like protein
      pfam11882
      Location:460783
      DUF3402; Domain of unknown function (DUF3402)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      107519848..107539010 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)