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    Mall mal, T cell differentiation protein-like [ Mus musculus (house mouse) ]

    Gene ID: 228576, updated on 11-Apr-2024

    Summary

    Official Symbol
    Mallprovided by MGI
    Official Full Name
    mal, T cell differentiation protein-likeprovided by MGI
    Primary source
    MGI:MGI:2385152
    See related
    Ensembl:ENSMUSG00000027377 AllianceGenome:MGI:2385152
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    BENE
    Summary
    Predicted to be a structural constituent of myelin sheath. Predicted to be involved in myelination. Predicted to be located in several cellular components, including Golgi membrane; clathrin-coated vesicle; and membrane raft. Predicted to be integral component of membrane. Is expressed in naris. Orthologous to human MALL (mal, T cell differentiation protein like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in duodenum adult (RPKM 163.5), small intestine adult (RPKM 154.5) and 4 other tissues See more
    Orthologs
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    Genomic context

    Location:
    2 F1; 2 62.08 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (127546310..127571817, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (127704386..127730772, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene poly (A) polymerase alpha pseudogene Neighboring gene predicted gene 14244 Neighboring gene STARR-seq mESC enhancer starr_05629 Neighboring gene nephronophthisis 1 (juvenile) homolog (human) Neighboring gene STARR-seq mESC enhancer starr_05630 Neighboring gene mitoregulin

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 

    General gene information

    Markers

    Clone Names

    • MGC19097

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural constituent of myelin sheath IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in myelination IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in clathrin-coated vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasmic vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in membrane raft ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_145532.4NP_663507.1  MAL-like protein

      See identical proteins and their annotated locations for NP_663507.1

      Status: VALIDATED

      Source sequence(s)
      AL844204
      Consensus CDS
      CCDS16708.1
      UniProtKB/Swiss-Prot
      Q3TQ65, Q91X49
      Related
      ENSMUSP00000028856.3, ENSMUST00000028856.3
      Conserved Domains (1) summary
      pfam01284
      Location:25149
      MARVEL; Membrane-associating domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      127546310..127571817 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)