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    Cstpp1 centriolar satellite-associated tubulin polyglutamylase complex regulator 1 [ Mus musculus (house mouse) ]

    Gene ID: 228356, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Cstpp1provided by MGI
    Official Full Name
    centriolar satellite-associated tubulin polyglutamylase complex regulator 1provided by MGI
    Primary source
    MGI:MGI:1915079
    See related
    Ensembl:ENSMUSG00000040591 AllianceGenome:MGI:1915079
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    1110051M20Rik
    Summary
    Orthologous to human C11orf49 (chromosome 11 open reading frame 49). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 12.2), cerebellum adult (RPKM 11.4) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    2 E1; 2 50.63 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (91103585..91275059, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (91273240..91444714, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene predicted gene, 31054 Neighboring gene STARR-positive B cell enhancer ABC_E3385 Neighboring gene protein kinase C and casein kinase substrate in neurons 3 Neighboring gene ADP-ribosylation factor GTPase activating protein 2 Neighboring gene CapStarr-seq enhancer MGSCv37_chr2:91148974-91149175 Neighboring gene STARR-seq mESC enhancer starr_05115 Neighboring gene predicted gene 13787 Neighboring gene STARR-positive B cell enhancer ABC_E9518 Neighboring gene low density lipoprotein receptor-related protein 4 Neighboring gene predicted gene 13770

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method. Piao Y, et al. Genome Res, 2001 Sep. PMID 11544199, Free PMC Article
    2. A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. Hansen J, et al. Proc Natl Acad Sci U S A, 2003 Aug 19. PMID 12904583, Free PMC Article
    3. Libraries enriched for alternatively spliced exons reveal splicing patterns in melanocytes and melanomas. Watahiki A, et al. Nat Methods, 2004 Dec. PMID 15782199
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC4707, MGC40841

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables protein-macromolecule adaptor activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in regulation of protein complex stability ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in centriolar satellite ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in microtubule IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    centriolar satellite-associated tubulin polyglutamylase complex regulator 1
    Names
    UPF0705 protein C11orf49 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001311144.1 → NP_001298073.1  centriolar satellite-associated tubulin polyglutamylase complex regulator 1 isoform 1

      See identical proteins and their annotated locations for NP_001298073.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes isoform (1).
      Source sequence(s)
      AL732478, BC089006
      Consensus CDS
      CCDS79823.1
      UniProtKB/Swiss-Prot
      Q8BHR8
      Related
      ENSMUSP00000067770.8, ENSMUST00000064652.14

    2. NM_175123.5 → NP_780332.1  centriolar satellite-associated tubulin polyglutamylase complex regulator 1 isoform 2

      See identical proteins and their annotated locations for NP_780332.1

      Status: VALIDATED

      Source sequence(s)
      AL732478
      Consensus CDS
      CCDS16431.1
      UniProtKB/Swiss-Prot
      Q3TPK0, Q5HZI4, Q8BHR8
      UniProtKB/TrEMBL
      Q810Q1
      Related
      ENSMUSP00000099654.5, ENSMUST00000102594.11

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      91103585..91275059 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036161262.1 → XP_036017155.1  centriolar satellite-associated tubulin polyglutamylase complex regulator 1 isoform X1

      UniProtKB/TrEMBL
      A2AII6
      Related
      ENSMUSP00000092431.3, ENSMUST00000094835.9

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_153797.1: Suppressed sequence

      Description
      NM_153797.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8BHR8.1 GenPept UniProtKB/Swiss-Prot:Q8BHR8

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
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