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    Zfp61 zinc finger protein 61 [ Mus musculus (house mouse) ]

    Gene ID: 22719, updated on 30-Apr-2024

    Summary

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    Official Symbol
    Zfp61provided by MGI
    Official Full Name
    zinc finger protein 61provided by MGI
    Primary source
    MGI:MGI:99663
    See related
    Ensembl:ENSMUSG00000050605 AllianceGenome:MGI:99663
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be active in nucleus. Is expressed in bladder; female associated reproductive structure; ovary; ureter; and urethra of female. Orthologous to human ZNF226 (zinc finger protein 226). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in CNS E11.5 (RPKM 6.6), CNS E14 (RPKM 6.1) and 25 other tissues See more
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    Genomic context

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    Location:
    7 A3; 7 10.27 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (23990470..24003273, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (24291045..24303840, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene zinc finger protein 51 pseudogene Neighboring gene predicted gene, 50477 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:25084411-25084520 Neighboring gene zinc finger protein 94 Neighboring gene predicted gene, 51470 Neighboring gene CapStarr-seq enhancer MGSCv37_chr7:25101698-25101895 Neighboring gene predicted gene 44513

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A mouse cDNA encoding a protein with zinc-fingers and a KRAB domain shows similarity to human profilaggrin. Brady JP, et al. Gene, 1994 Nov 18. PMID 7959006
    2. Chromosomal localization of the genes for five zinc finger proteins expressed in mouse lens. Danciger M, et al. Genomics, 1995 Jul 1. PMID 7590745
    3. A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract. Wiese CB, et al. Front Neurosci, 2012. PMID 22988430, Free PMC Article
    4. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
    5. Mouse brain organization revealed through direct genome-scale TF expression analysis. Gray PA, et al. Science, 2004 Dec 24. PMID 15618518

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    General gene information

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    Homology

    General protein information

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    Preferred Names
    zinc finger protein 155

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009561.2 → NP_033587.2  zinc finger protein 155

      See identical proteins and their annotated locations for NP_033587.2

      Status: VALIDATED

      Source sequence(s)
      AK149960, BY271078, BY420227
      Consensus CDS
      CCDS39829.1
      UniProtKB/TrEMBL
      Q923D1
      Related
      ENSMUSP00000076954.8, ENSMUST00000077780.14
      Conserved Domains (3) summary
      smart00349
      Location:4 → 63
      KRAB; krueppel associated box
      COG5048
      Location:338 → 526
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:341 → 361
      ZF_C2H2; C2H2 Zn finger [structural motif]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      23990470..24003273 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030242398.2 → XP_030098258.1  zinc finger protein 155 isoform X1

      UniProtKB/TrEMBL
      Q923D1
      Conserved Domains (3) summary
      smart00349
      Location:4 → 63
      KRAB; krueppel associated box
      COG5048
      Location:338 → 526
      COG5048; FOG: Zn-finger [General function prediction only]
      sd00017
      Location:341 → 361
      ZF_C2H2; C2H2 Zn finger [structural motif]
    Nucleotide Protein Strain
    Heading Accession and Version

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