U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Slc23a3 solute carrier family 23 (nucleobase transporters), member 3 [ Mus musculus (house mouse) ]

    Gene ID: 22626, updated on 5-Mar-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Slc23a3provided by MGI
    Official Full Name
    solute carrier family 23 (nucleobase transporters), member 3provided by MGI
    Primary source
    MGI:MGI:104516
    See related
    Ensembl:ENSMUSG00000026205 AllianceGenome:MGI:104516
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SVCT3; Yspl1
    Summary
    Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be located in cytoplasm and membrane. Predicted to be integral component of membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human SLC23A3 (solute carrier family 23 member 3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in placenta adult (RPKM 6.4), kidney adult (RPKM 4.5) and 15 other tissues See more
    Orthologs
    human all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    1 C4; 1 38.6 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (75102185..75112113, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (75125541..75135223, complement)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene Indian hedgehog Neighboring gene non-homologous end joining factor 1 Neighboring gene STARR-seq mESC enhancer starr_01350 Neighboring gene STARR-seq mESC enhancer starr_01351 Neighboring gene STARR-seq mESC enhancer starr_01352 Neighboring gene cyclin Pas1/PHO80 domain containing 1 Neighboring gene reticulophagy regulator family member 2

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. A new approach to the study of haematopoietic development in the yolk sac and embryoid bodies. Guimarães MJ, et al. Development, 1995 Oct. PMID 7588067
    2. Interactome mapping of the phosphatidylinositol 3-kinase-mammalian target of rapamycin pathway identifies deformed epidermal autoregulatory factor-1 as a new glycogen synthase kinase-3 interactor. Pilot-Storck F, et al. Mol Cell Proteomics, 2010 Jul. PMID 20368287, Free PMC Article
    3. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. The transcriptional landscape of the mammalian genome. Carninci P, et al. Science, 2005 Sep 2. PMID 16141072

    See all (7) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

    Go to the top of the page Help

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Interactions

    Go to the top of the page Help
    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Go to the top of the page Help

    Markers

    Homology

    Clone Names

    • MGC143681, MGC143682

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    enables transmembrane transporter activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables transporter activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    involved_in hypoxanthine transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

    Go to the top of the page Help
    Preferred Names
    solute carrier family 23 member 3
    Names
    Na(+)/L-ascorbic acid transporter 3
    YSPL-1
    sodium-dependent vitamin C transporter 3
    yolk sac permease-like molecule 1

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_194333.3 → NP_919314.2  solute carrier family 23 member 3

      See identical proteins and their annotated locations for NP_919314.2

      Status: VALIDATED

      Source sequence(s)
      BC094893, BC117790, CJ065822
      Consensus CDS
      CCDS15062.1
      UniProtKB/Swiss-Prot
      Q149H3, Q4VBX5, Q60850, Q60851, Q60852, Q60853, Q78E82, Q78E83, Q78E84
      UniProtKB/TrEMBL
      A0A0R4J067
      Related
      ENSMUSP00000027405.5, ENSMUST00000027405.6
      Conserved Domains (2) summary
      pfam00860
      Location:83 → 476
      Xan_ur_permease; Permease family
      cl23746
      Location:87 → 482
      HCO3_cotransp; HCO3- transporter family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      75102185..75112113 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036163732.1 → XP_036019625.1  solute carrier family 23 member 3 isoform X2

      UniProtKB/Swiss-Prot
      Q149H3, Q4VBX5, Q60850, Q60851, Q60852, Q60853, Q78E82, Q78E83, Q78E84
      Conserved Domains (1) summary
      pfam00860
      Location:6 → 370
      Xan_ur_permease; Permease family

    2. XM_006496481.2 → XP_006496544.1  solute carrier family 23 member 3 isoform X4

      Conserved Domains (1) summary
      cl23746
      Location:16 → 259
      Xan_ur_permease; Permease family

    3. XM_006496480.2 → XP_006496543.1  solute carrier family 23 member 3 isoform X3

      Conserved Domains (1) summary
      cl23746
      Location:83 → 332
      Xan_ur_permease; Permease family

    4. XM_030253070.1 → XP_030108930.1  solute carrier family 23 member 3 isoform X5

      UniProtKB/Swiss-Prot
      Q149H3, Q4VBX5, Q60850, Q60851, Q60852, Q60853, Q78E82, Q78E83, Q78E84
      Conserved Domains (1) summary
      cl23746
      Location:83 → 359
      Xan_ur_permease; Permease family

    5. XM_006496479.2 → XP_006496542.1  solute carrier family 23 member 3 isoform X1

      UniProtKB/Swiss-Prot
      Q149H3, Q4VBX5, Q60850, Q60851, Q60852, Q60853, Q78E82, Q78E83, Q78E84
      Conserved Domains (1) summary
      pfam00860
      Location:83 → 476
      Xan_ur_permease; Permease family

    RNA

    1. XR_373540.3 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q60850.1 GenPept UniProtKB/Swiss-Prot:Q60850

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Tools
    Miscellaneous