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    Prelid3a PRELI domain containing 3A [ Mus musculus (house mouse) ]

    Gene ID: 225655, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Prelid3aprovided by MGI
    Official Full Name
    PRELI domain containing 3Aprovided by MGI
    Primary source
    MGI:MGI:2442865
    See related
    Ensembl:ENSMUSG00000024530 AllianceGenome:MGI:2442865
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Slmo1; A230074A19Rik
    Summary
    Predicted to enable phosphatidic acid transfer activity. Predicted to be involved in phospholipid transport. Predicted to act upstream of or within lipid transport. Located in mitochondrion. Orthologous to human PRELID3A (PRELI domain containing 3A). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in cortex adult (RPKM 7.1), frontal lobe adult (RPKM 7.1) and 10 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    18 E1; 18 39.99 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (67595119..67613651)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (67462049..67480581)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene tubulin, beta 6 class V Neighboring gene AFG3-like AAA ATPase 2 Neighboring gene STARR-positive B cell enhancer ABC_E3234 Neighboring gene spire type actin nucleation factor 1 Neighboring gene STARR-seq mESC enhancer starr_44904 Neighboring gene STARR-seq mESC enhancer starr_44905 Neighboring gene STARR-seq mESC enhancer starr_44907 Neighboring gene predicted gene, 17669 Neighboring gene STARR-positive B cell enhancer mm9_chr18:67771962-67772263 Neighboring gene centrosomal protein 76

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A mitochondrial protein compendium elucidates complex I disease biology. Pagliarini DJ, et al. Cell, 2008 Jul 11. PMID 18614015, Free PMC Article
    2. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808
    3. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    4. Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. Zambrowicz BP, et al. Proc Natl Acad Sci U S A, 2003 Nov 25. PMID 14610273, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Clone Names

    • MGC28728

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables phosphatidic acid transfer activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables phosphatidic acid transfer activity ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within lipid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in phospholipid transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in phospholipid transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in mitochondrial intermembrane space IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in mitochondrion HDA PubMed 

    General protein information

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    Preferred Names
    PRELI domain containing protein 3A
    Names
    protein slowmo homolog 1
    slowmo homolog 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_144867.2 → NP_659116.1  PRELI domain containing protein 3A

      See identical proteins and their annotated locations for NP_659116.1

      Status: VALIDATED

      Source sequence(s)
      AC154125, AK143220, BY741062
      Consensus CDS
      CCDS37848.1
      UniProtKB/Swiss-Prot
      Q8VE85
      Related
      ENSMUSP00000025411.8, ENSMUST00000025411.9
      Conserved Domains (1) summary
      pfam04707
      Location:15 → 170
      PRELI; PRELI-like family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      67595119..67613651
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006525896.4 → XP_006525959.1  PRELI domain containing protein 3A isoform X2

      Conserved Domains (1) summary
      pfam04707
      Location:15 → 156
      PRELI; PRELI-like family

    2. XM_006525897.5 → XP_006525960.1  PRELI domain containing protein 3A isoform X3

      See identical proteins and their annotated locations for XP_006525960.1

      UniProtKB/Swiss-Prot
      Q8VE85
      Conserved Domains (1) summary
      pfam04707
      Location:15 → 170
      PRELI; PRELI-like family

    3. XM_006525895.5 → XP_006525958.1  PRELI domain containing protein 3A isoform X1

      UniProtKB/TrEMBL
      A0A494B9F8
      Related
      ENSMUSP00000157593.2, ENSMUST00000235414.2
      Conserved Domains (1) summary
      pfam04707
      Location:15 → 155
      PRELI; PRELI-like family

    RNA

    1. XR_385989.4 RNA Sequence

    2. XR_001782357.3 RNA Sequence

    3. XR_001782358.3 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VE85.1 GenPept UniProtKB/Swiss-Prot:Q8VE85

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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