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    Rrp36 ribosomal RNA processing 36 [ Mus musculus (house mouse) ]

    Gene ID: 224823, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Rrp36provided by MGI
    Official Full Name
    ribosomal RNA processing 36provided by MGI
    Primary source
    MGI:MGI:2385053
    See related
    Ensembl:ENSMUSG00000023971 AllianceGenome:MGI:2385053
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to act upstream of or within ribosome biogenesis. Predicted to be located in nucleoplasm. Predicted to be part of 90S preribosome. Predicted to be active in nucleolus. Orthologous to human RRP36 (ribosomal RNA processing 36). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in placenta adult (RPKM 14.7), ovary adult (RPKM 13.9) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    17 C; 17 22.9 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (46977249..46985252, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (46666323..46674326, complement)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene kinesin light chain 4 Neighboring gene STARR-positive B cell enhancer ABC_E7536 Neighboring gene mitochondrial ribosomal protein L2 Neighboring gene cullin 7 Neighboring gene STARR-seq mESC enhancer starr_42676 Neighboring gene kelch domain containing 3 Neighboring gene STARR-positive B cell enhancer mm9_chr17:46817738-46818039 Neighboring gene male enhanced antigen 1 Neighboring gene protein phosphatase 2, regulatory subunit B', delta Neighboring gene STARR-positive B cell enhancer ABC_E7538

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Evolutionarily conserved function of RRP36 in early cleavages of the pre-rRNA and production of the 40S ribosomal subunit. Gérus M, et al. Mol Cell Biol, 2010 Mar. PMID 20038530, Free PMC Article
    2. A molecular profile of a hematopoietic stem cell niche. Hackney JA, et al. Proc Natl Acad Sci U S A, 2002 Oct 1. PMID 12226475, Free PMC Article
    3. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    4. Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Hansen GM, et al. Genome Res, 2008 Oct. PMID 18799693, Free PMC Article
    5. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Pathways from PubChem

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    General gene information

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    Homology

    Clone Names

    • MGC19067

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    involved_in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in rRNA processing ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in ribosomal small subunit biogenesis ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within ribosome biogenesis IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    part_of 90S preribosome IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    ribosomal RNA processing protein 36 homolog
    Names
    RNA processing factor
    ribosomal RNA processing 36 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001368622.1 → NP_001355551.1  ribosomal RNA processing protein 36 homolog isoform 2

      Status: VALIDATED

      Source sequence(s)
      CT030702
      UniProtKB/TrEMBL
      A0A0R4J045
      Conserved Domains (1) summary
      pfam06102
      Location:41 → 195
      RRP36; rRNA biogenesis protein RRP36

    2. NM_144857.2 → NP_659106.2  ribosomal RNA processing protein 36 homolog isoform 1

      Status: VALIDATED

      Source sequence(s)
      BE647409, BQ833497, CT030702
      Consensus CDS
      CCDS37639.2
      UniProtKB/TrEMBL
      A0A0R4J045, A0A3B2WB30
      Related
      ENSMUSP00000156646.2, ENSMUST00000233136.2
      Conserved Domains (1) summary
      pfam06102
      Location:76 → 230
      RRP36; rRNA biogenesis protein RRP36

    RNA

    1. NR_160853.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      BE647409, BQ833497, CT030702

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      46977249..46985252 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3UFY0.1 GenPept UniProtKB/Swiss-Prot:Q3UFY0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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