U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Bnip1 BCL2/adenovirus E1B interacting protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 224630, updated on 11-Apr-2024

    Summary

    Official Symbol
    Bnip1provided by MGI
    Official Full Name
    BCL2/adenovirus E1B interacting protein 1provided by MGI
    Primary source
    MGI:MGI:109328
    See related
    Ensembl:ENSMUSG00000024191 AllianceGenome:MGI:109328
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Sec20; 2010005M06Rik; 5930429G21Rik
    Summary
    Predicted to enable SNAP receptor activity. Predicted to be involved in endoplasmic reticulum membrane fusion and retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum. Predicted to act upstream of or within apoptotic process. Predicted to be located in several cellular components, including COPI-coated vesicle; mitochondrial membrane; and nuclear envelope. Predicted to be part of SNARE complex. Predicted to be active in endoplasmic reticulum. Orthologous to human BNIP1 (BCL2 interacting protein 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 6.5), CNS E18 (RPKM 6.4) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Location:
    17 A3.3; 17 13.56 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 17 NC_000083.7 (26999876..27011539)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 17 NC_000083.6 (26781079..26792521)

    Chromosome 17 - NC_000083.7Genomic Context describing neighboring genes Neighboring gene ATPase, H+ transporting, lysosomal V0 subunit E Neighboring gene CREB3 regulatory factor Neighboring gene STARR-positive B cell enhancer ABC_E3193 Neighboring gene STARR-positive B cell enhancer ABC_E2474 Neighboring gene STARR-positive B cell enhancer ABC_E8660 Neighboring gene STARR-seq mESC enhancer starr_42133 Neighboring gene STARR-seq mESC enhancer starr_42134 Neighboring gene VISTA enhancer mm1645 Neighboring gene NK2 homeobox 5 Neighboring gene predicted gene, 53221

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (5) 
    • Endonuclease-mediated (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC41600

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables SNAP receptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables calcium-induced calcium release activity ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in COPI-coated vesicle ISO
    Inferred from Sequence Orthology
    more info
     
    part_of SNARE complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of SNARE complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial membrane ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in mitochondrial outer membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nuclear envelope ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    vesicle transport protein SEC20
    Names
    BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP1
    BCL2/adenovirus E1B interacting protein 1, NIP1
    SNARE protein SEC20

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_172149.5NP_742161.4  vesicle transport protein SEC20

      See identical proteins and their annotated locations for NP_742161.4

      Status: VALIDATED

      Source sequence(s)
      AW060311, AY547731, CV560804
      Consensus CDS
      CCDS28555.1
      UniProtKB/Swiss-Prot
      B0V2Q1, Q5M9M2, Q6QD59
      Related
      ENSMUSP00000015725.9, ENSMUST00000015725.16
      Conserved Domains (1) summary
      cd15865
      Location:132224
      SNARE_SEC20; SNARE motif of SEC20

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000083.7 Reference GRCm39 C57BL/6J

      Range
      26999876..27011539
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036160513.1XP_036016406.1  vesicle transport protein SEC20 isoform X1

      UniProtKB/TrEMBL
      F6QGF9
      Related
      ENSMUSP00000116284.2, ENSMUST00000137989.2
    2. XM_030249681.2XP_030105541.1  vesicle transport protein SEC20 isoform X2

      Conserved Domains (1) summary
      cd15865
      Location:45137
      SNARE_SEC20; SNARE motif of SEC20
    3. XM_036160514.1XP_036016407.1  vesicle transport protein SEC20 isoform X2

      Conserved Domains (1) summary
      cd15865
      Location:45137
      SNARE_SEC20; SNARE motif of SEC20