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    Map3k7cl Map3k7 C-terminal like [ Mus musculus (house mouse) ]

    Gene ID: 224419, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Map3k7clprovided by MGI
    Official Full Name
    Map3k7 C-terminal likeprovided by MGI
    Primary source
    MGI:MGI:2446584
    See related
    Ensembl:ENSMUSG00000025610 AllianceGenome:MGI:2446584
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ORF63; Tak1l; C21orf7
    Summary
    Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; limb; and nervous system. Orthologous to human MAP3K7CL (MAP3K7 C-terminal like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in kidney adult (RPKM 11.5), ovary adult (RPKM 2.1) and 7 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Map3k7cl in Genome Data Viewer
    Location:
    16 C3.3; 16 49.58 cM
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 16 NC_000082.7 (87350208..87392224)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 16 NC_000082.6 (87553330..87595336)

    Chromosome 16 - NC_000082.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 24891 Neighboring gene ribosomal protein L31, pseudogene 4 Neighboring gene STARR-seq mESC enhancer starr_41399 Neighboring gene STARR-seq mESC enhancer starr_41400 Neighboring gene predicted gene, 41485 Neighboring gene predicted gene, 22808

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. From PREDs and open reading frames to cDNA isolation: revisiting the human chromosome 21 transcription map. Reymond A, et al. Genomics, 2001 Nov. PMID 11707072
    2. A gene expression map of human chromosome 21 orthologues in the mouse. Gitton Y, et al. Nature, 2002 Dec 5. PMID 12466855
    3. Human chromosome 21 gene expression atlas in the mouse. Reymond A, et al. Nature, 2002 Dec 5. PMID 12466854
    4. A systems approach reveals that the myogenesis genome network is regulated by the transcriptional repressor RP58. Yokoyama S, et al. Dev Cell, 2009 Dec. PMID 20059953, Free PMC Article
    5. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    MAP3K7 C-terminal-like protein
    Names
    TAK1-like protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001417078.1 → NP_001404007.1  MAP3K7 C-terminal-like protein

      Status: VALIDATED

      Source sequence(s)
      AC154631, CT025527
      UniProtKB/Swiss-Prot
      P58500
      UniProtKB/TrEMBL
      Q544C0

    2. NM_144854.3 → NP_659103.1  MAP3K7 C-terminal-like protein

      See identical proteins and their annotated locations for NP_659103.1

      Status: VALIDATED

      Source sequence(s)
      AC154631, CT025527
      Consensus CDS
      CCDS28292.1
      UniProtKB/Swiss-Prot
      P58500
      UniProtKB/TrEMBL
      Q544C0
      Related
      ENSMUSP00000026700.8, ENSMUST00000026700.8
      Conserved Domains (1) summary
      TIGR04211
      Location:39 → 142
      SH3_and_anchor; SH3 domain protein

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000082.7 Reference GRCm39 C57BL/6J

      Range
      87350208..87392224
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006523007.5 → XP_006523070.1  MAP3K7 C-terminal-like protein isoform X2

      Conserved Domains (1) summary
      TIGR04211
      Location:9 → 87
      SH3_and_anchor; SH3 domain protein
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P58500.1 GenPept UniProtKB/Swiss-Prot:P58500

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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