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    Slc35a2 solute carrier family 35 (UDP-galactose transporter), member A2 [ Mus musculus (house mouse) ]

    Gene ID: 22232, updated on 3-Apr-2024

    Summary

    Official Symbol
    Slc35a2provided by MGI
    Official Full Name
    solute carrier family 35 (UDP-galactose transporter), member A2provided by MGI
    Primary source
    MGI:MGI:1345297
    See related
    Ensembl:ENSMUSG00000031156 AllianceGenome:MGI:1345297
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    UGT; Had1; Sfc8; Had-1; Ugalt
    Summary
    Enables UDP-galactose transmembrane transporter activity. Acts upstream of or within UDP-galactose transmembrane transport. Located in Golgi membrane. Is expressed in several structures, including genitourinary system; heart; liver; lung; and spleen. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIm. Orthologous to human SLC35A2 (solute carrier family 35 member A2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in colon adult (RPKM 48.8), adrenal adult (RPKM 22.5) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    Location:
    X A1.1; X 3.56 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (7750189..7760699)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (7883921..7894492)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene STARR-seq mESC enhancer starr_46674 Neighboring gene OTU domain containing 5 Neighboring gene STARR-positive B cell enhancer ABC_E11045 Neighboring gene proviral integration site 2 Neighboring gene STARR-positive B cell enhancer ABC_E7684 Neighboring gene polyglutamine binding protein 1 Neighboring gene translocase of inner mitochondrial membrane 17b

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (2) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in Golgi membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    is_active_in Golgi membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    UDP-galactose translocator
    Names
    UDP-Gal-Tr
    UDP-galactose transporter
    mUGT1
    solute carrier family (UDP-N-acetylglucosamine transporter), member 2
    solute carrier family 35 (UDP-galactose transporter) member 2
    solute carrier family 35 (UDP-galactose transporter), member 2
    solute carrier family 35 member A2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001083937.2NP_001077406.1  UDP-galactose translocator isoform 2

      See identical proteins and their annotated locations for NP_001077406.1

      Status: VALIDATED

      Source sequence(s)
      AL671978
      Consensus CDS
      CCDS52987.1
      UniProtKB/Swiss-Prot
      Q9R0M8
      UniProtKB/TrEMBL
      Q3UIP1, Q9JIH0
      Related
      ENSMUSP00000111324.5, ENSMUST00000115660.12
      Conserved Domains (2) summary
      TIGR00803
      Location:114338
      nst; UDP-galactose transporter
      pfam04142
      Location:31339
      Nuc_sug_transp; Nucleotide-sugar transporter
    2. NM_001426060.1NP_001412989.1  UDP-galactose translocator isoform 3

      Status: VALIDATED

      Source sequence(s)
      AL671978
    3. NM_001426061.1NP_001412990.1  UDP-galactose translocator isoform 4

      Status: VALIDATED

      Source sequence(s)
      AL671978
      UniProtKB/TrEMBL
      A0A140LI17
    4. NM_001426062.1NP_001412991.1  UDP-galactose translocator isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL671978
    5. NM_001426063.1NP_001412992.1  UDP-galactose translocator isoform 6

      Status: VALIDATED

      Source sequence(s)
      AL671978
    6. NM_001426064.1NP_001412993.1  UDP-galactose translocator isoform 7

      Status: VALIDATED

      Source sequence(s)
      AL671978
    7. NM_001426065.1NP_001412994.1  UDP-galactose translocator isoform 8

      Status: VALIDATED

      Source sequence(s)
      AL671978
    8. NM_078484.3NP_511039.2  UDP-galactose translocator isoform 1

      Status: VALIDATED

      Source sequence(s)
      AL671978
      Consensus CDS
      CCDS52986.1
      UniProtKB/TrEMBL
      A2AER4, Q9JIH0
      Related
      ENSMUSP00000111327.4, ENSMUST00000115663.10
      Conserved Domains (2) summary
      TIGR00803
      Location:114338
      nst; UDP-galactose transporter
      pfam04142
      Location:31339
      Nuc_sug_transp; Nucleotide-sugar transporter

    RNA

    1. NR_189662.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL671978
    2. NR_189663.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL671978
    3. NR_189664.1 RNA Sequence

      Status: VALIDATED

      Source sequence(s)
      AL671978

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      7750189..7760699
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030251303.2XP_030107163.2  UDP-galactose translocator isoform X1

      Conserved Domains (1) summary
      pfam04142
      Location:1267
      Nuc_sug_transp; Nucleotide-sugar transporter
    2. XM_006527584.4XP_006527647.1  UDP-galactose translocator isoform X2

      Conserved Domains (1) summary
      pfam04142
      Location:1181
      Nuc_sug_transp; Nucleotide-sugar transporter