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    Tex2 testis expressed gene 2 [ Mus musculus (house mouse) ]

    Gene ID: 21763, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Tex2provided by MGI
    Official Full Name
    testis expressed gene 2provided by MGI
    Primary source
    MGI:MGI:102465
    See related
    Ensembl:ENSMUSG00000040548 AllianceGenome:MGI:102465
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Taz4; Def-5; 4930568E07Rik
    Summary
    Predicted to enable lipid binding activity. Predicted to act upstream of or within lipid transport. Predicted to be located in membrane and nucleus. Predicted to be integral component of membrane. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including alimentary system; genitourinary system; liver; nervous system; and respiratory system. Orthologous to human TEX2 (testis expressed 2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in testis adult (RPKM 83.3), placenta adult (RPKM 18.2) and 19 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tex2 in Genome Data Viewer
    Location:
    11 E1; 11 69.46 cM
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (106392965..106504259, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (106502139..106613433, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA, C/D box 104 Neighboring gene predicted gene, 36220 Neighboring gene predicted gene, 22711 Neighboring gene nucleophosmin 1 pseudogene Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:106397706-106397815 Neighboring gene STARR-seq mESC enhancer starr_30931 Neighboring gene STARR-positive B cell enhancer ABC_E5288 Neighboring gene STARR-positive B cell enhancer ABC_E1150 Neighboring gene platelet/endothelial cell adhesion molecule 1 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:106535909-106536110 Neighboring gene STARR-seq mESC enhancer starr_30943 Neighboring gene STARR-seq mESC enhancer starr_30946 Neighboring gene predicted gene, 51950

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Def-2, -3, -6 and -8, novel mouse genes differentially expressed in the haemopoietic system. Hotfilder M, et al. Br J Haematol, 1999 Aug. PMID 10460589
    2. Chromosomal assignment of three novel mouse genes expressed in testicular cells. Lemaire L, et al. Genomics, 1994 May 15. PMID 8088835
    3. Neuronal ceroid lipofuscinosis (nclf), a new disorder of the mouse linked to chromosome 9. Bronson RT, et al. Am J Med Genet, 1998 May 26. PMID 9600738
    4. Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations. Munton RP, et al. Mol Cell Proteomics, 2007 Feb. PMID 17114649
    5. Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. Federspiel JD, et al. Mol Cell Proteomics, 2019 Aug 9. PMID 31040226, Free PMC Article

    See all (30) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (2) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables lipid binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    acts_upstream_of_or_within lipid transport IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in endoplasmic reticulum IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    testis-expressed protein 2
    Names
    testis-expressed sequence 2 protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198292.3 → NP_938034.2  testis-expressed protein 2

      See identical proteins and their annotated locations for NP_938034.2

      Status: VALIDATED

      Source sequence(s)
      AK129434, BY667615, CB594125
      Consensus CDS
      CCDS25557.1
      UniProtKB/Swiss-Prot
      B1ATR1, Q6ZPJ0
      Related
      ENSMUSP00000041985.8, ENSMUST00000042780.14
      Conserved Domains (1) summary
      pfam10296
      Location:826 → 915
      DUF2404; Putative integral membrane protein conserved region (DUF2404)

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      106392965..106504259 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036156623.1 → XP_036012516.1  testis-expressed protein 2 isoform X2

    2. XM_006533145.2 → XP_006533208.1  testis-expressed protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006533208.1

      UniProtKB/Swiss-Prot
      B1ATR1, Q6ZPJ0
      Conserved Domains (1) summary
      pfam10296
      Location:826 → 915
      DUF2404; Putative integral membrane protein conserved region (DUF2404)

    3. XM_036156622.1 → XP_036012515.1  testis-expressed protein 2 isoform X2

    4. XM_006533146.5 → XP_006533209.1  testis-expressed protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006533209.1

      UniProtKB/Swiss-Prot
      B1ATR1, Q6ZPJ0
      Conserved Domains (1) summary
      pfam10296
      Location:826 → 915
      DUF2404; Putative integral membrane protein conserved region (DUF2404)

    5. XM_006533148.5 → XP_006533211.1  testis-expressed protein 2 isoform X2

      Conserved Domains (1) summary
      pfam10296
      Location:826 → 915
      DUF2404; Putative integral membrane protein conserved region (DUF2404)

    6. XM_036156621.1 → XP_036012514.1  testis-expressed protein 2 isoform X1

      UniProtKB/Swiss-Prot
      B1ATR1, Q6ZPJ0

    7. XM_006533147.4 → XP_006533210.1  testis-expressed protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006533210.1

      UniProtKB/Swiss-Prot
      B1ATR1, Q6ZPJ0
      Conserved Domains (1) summary
      pfam10296
      Location:826 → 915
      DUF2404; Putative integral membrane protein conserved region (DUF2404)

    8. XM_006533144.4 → XP_006533207.1  testis-expressed protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006533207.1

      UniProtKB/Swiss-Prot
      B1ATR1, Q6ZPJ0
      Conserved Domains (1) summary
      pfam10296
      Location:826 → 915
      DUF2404; Putative integral membrane protein conserved region (DUF2404)

    9. XM_006533143.4 → XP_006533206.1  testis-expressed protein 2 isoform X1

      See identical proteins and their annotated locations for XP_006533206.1

      UniProtKB/Swiss-Prot
      B1ATR1, Q6ZPJ0
      Conserved Domains (1) summary
      pfam10296
      Location:826 → 915
      DUF2404; Putative integral membrane protein conserved region (DUF2404)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q6ZPJ0.2 GenPept UniProtKB/Swiss-Prot:Q6ZPJ0

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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