U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    Myo15b myosin XVB [ Mus musculus (house mouse) ]

    Gene ID: 217328, updated on 5-Mar-2024

    Summary

    Go to the top of the page Help
    Official Symbol
    Myo15bprovided by MGI
    Official Full Name
    myosin XVBprovided by MGI
    Primary source
    MGI:MGI:2685534
    See related
    Ensembl:ENSMUSG00000034427 AllianceGenome:MGI:2685534
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm688; Gm886; mKIAA1783; E330039G21Rik
    Summary
    Located in brush border. Is expressed in genitourinary system. Orthologous to human MYO15B (myosin XVB). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in small intestine adult (RPKM 116.1), colon adult (RPKM 107.2) and 3 other tissues See more
    Orthologs
    human all
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    Go to the top of the page Help
    Location:
    11 E2; 11 80.91 cM
    Exon count:
    66
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (115749002..115783443)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (115857925..115892617)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E3039 Neighboring gene tRNA splicing endonuclease subunit 54 Neighboring gene STARR-seq mESC enhancer starr_31175 Neighboring gene LLGL2 scribble cell polarity complex component Neighboring gene STARR-seq mESC enhancer starr_31178 Neighboring gene CapStarr-seq enhancer MGSCv37_chr11:115759828-115760025 Neighboring gene RecQ protein-like 5 Neighboring gene small integral membrane protein 5 Neighboring gene small integral membrane protein 6

    Genomic regions, transcripts, and products

    Go to the top of the page Help

    Go to nucleotide: Graphics FASTA GenBank

    Expression

    Go to the top of the page Help
    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    Go to the top of the pageHelp

    Related articles in PubMed

    1. Human myosin XVBP is a transcribed pseudogene. Boger ET, et al. J Muscle Res Cell Motil, 2001. PMID 11964073
    2. Expression of metanephric nephron-patterning genes in differentiating mesonephric tubules. Georgas KM, et al. Dev Dyn, 2011 Jun. PMID 21491542, Free PMC Article
    3. A new role for the architecture of microvillar actin bundles in apical retention of membrane proteins. Revenu C, et al. Mol Biol Cell, 2012 Jan. PMID 22114352, Free PMC Article
    4. Identification of anchor genes during kidney development defines ontological relationships, molecular subcompartments and regulatory pathways. Thiagarajan RD, et al. PLoS One, 2011 Feb 28. PMID 21386911, Free PMC Article
    5. Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries. Okazaki N, et al. DNA Res, 2004 Jun 30. PMID 15368895

    See all (16) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

    Go to the top of the page Help

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    General gene information

    Go to the top of the page Help

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in brush border IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

    Go to the top of the page Help
    Preferred Names
    myosin XVB

    NCBI Reference Sequences (RefSeq)

    Go to the top of the page Help

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001384233.2 → NP_001371162.1  myosin XVB

      Status: VALIDATED

      Source sequence(s)
      AL645647
      UniProtKB/TrEMBL
      I7HPW8
      Related
      ENSMUSP00000091439.6, ENSMUST00000093911.11
      Conserved Domains (8) summary
      PTZ00449
      Location:185 → 326
      PTZ00449; 104 kDa microneme/rhoptry antigen; Provisional
      cd14896
      Location:681 → 1360
      MYSc_Myo35; class XXXV myosin, motor domain
      pfam00373
      Location:2859 → 2968
      FERM_M; FERM central domain
      pfam00784
      Location:1575 → 1677
      MyTH4; MyTH4 domain
      cl02480
      Location:2617 → 2763
      MyTH4; MyTH4 domain
      cl17036
      Location:2469 → 2523
      SH3; Src Homology 3 domain superfamily
      cl17171
      Location:2964 → 3064
      PH-like; Pleckstrin homology-like domain
      cl28922
      Location:2784 → 2839
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      115749002..115783443
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036156604.1 → XP_036012497.1  myosin XVB isoform X1

      UniProtKB/TrEMBL
      A0A1Y7VNG3
      Related
      ENSMUSP00000152405.2, ENSMUST00000222123.2
      Conserved Domains (6) summary
      pfam00373
      Location:1401 → 1510
      FERM_M; FERM central domain
      pfam00784
      Location:117 → 219
      MyTH4; MyTH4 domain
      cl02480
      Location:1159 → 1305
      MyTH4; MyTH4 domain
      cl17036
      Location:1011 → 1065
      SH3; Src Homology 3 domain superfamily
      cl17171
      Location:1506 → 1606
      PH-like; Pleckstrin homology-like domain
      cl28922
      Location:1326 → 1381
      Ubiquitin_like_fold; Beta-grasp ubiquitin-like fold
    Nucleotide Protein Strain
    Heading Accession and Version

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

    Chemical Information
    Molecular Biology Databases
    Research Materials
    Miscellaneous