Klhl11 kelch-like 11 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Klhl11provided by MGI
Official Full Name: kelch-like 11provided by MGI
Primary source: MGI:MGI:2388648
See related: Ensembl:ENSMUSG00000048732 AllianceGenome:MGI:2388648
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Summary: Orthologous to human KLHL11 (kelch like family member 11). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Ubiquitous expression in testis adult (RPKM 8.3), cerebellum adult (RPKM 7.7) and 28 other tissues See more
Orthologs: human all
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Genomic context

Location:: 11 D; 11 63.47 cM

Exon count:: 3

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	11	NC_000077.7 (100347948..100363608, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	11	NC_000077.6 (100457122..100472782, complement)

Chromosome 11 - NC_000077.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info

Process	Evidence Code	Pubs
involved_in biological_process	ND No biological Data available more info

Component	Evidence Code	Pubs
is_active_in cellular_component	ND No biological Data available more info

General protein information

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Preferred Names: kelch-like protein 11

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_172565.2 → NP_766153.1 kelch-like protein 11 precursor

See identical proteins and their annotated locations for NP_766153.1

Status: VALIDATED

Source sequence(s)

AK029101

Consensus CDS

CCDS25424.1

UniProtKB/Swiss-Prot

Q3TDZ6, Q8CE33, Q91VP6

UniProtKB/TrEMBL

Q14DU1

Related

ENSMUSP00000054963.4, ENSMUST00000056665.4

Conserved Domains (6) summary

smart00612
Location:612 → 658

Kelch; Kelch domain

smart00225
Location:96 → 201

BTB; Broad-Complex, Tramtrack and Bric a brac

sd00038
Location:400 → 440

Kelch; KELCH repeat [structural motif]

pfam00651
Location:86 → 198

BTB; BTB/POZ domain

pfam01344
Location:443 → 487

Kelch_1; Kelch motif

pfam07707
Location:206 → 308

BACK; BTB And C-terminal Kelch