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    Lgalsl galectin like [ Mus musculus (house mouse) ]

    Gene ID: 216551, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Lgalslprovided by MGI
    Official Full Name
    galectin likeprovided by MGI
    Primary source
    MGI:MGI:1916114
    See related
    Ensembl:ENSMUSG00000042363 AllianceGenome:MGI:1916114
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Grpa; Hspc159; Lgalsla; A530071M23; 1110067D22Rik
    Summary
    Predicted to enable carbohydrate binding activity. Located in collagen-containing extracellular matrix. Is expressed in several structures, including cerebral cortex; dorsal root ganglion; retina nuclear layer; submandibular gland primordium; and thoracic segment skeleton. Orthologous to human LGALSL (galectin like). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in CNS E18 (RPKM 11.9), cerebellum adult (RPKM 10.4) and 26 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    11 A3.1; 11 13.53 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (20773355..20781916, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (20823355..20831916, complement)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene aftiphilin Neighboring gene RIKEN cDNA 4930434J08 gene Neighboring gene STARR-seq mESC enhancer starr_28821 Neighboring gene STARR-seq mESC enhancer starr_28822 Neighboring gene STARR-positive B cell enhancer mm9_chr11:20694243-20694543 Neighboring gene predicted gene, 32213 Neighboring gene predicted gene, 22807 Neighboring gene predicted gene, 53672

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Comparative transcription map of the wobbler critical region on mouse chromosome 11 and the homologous region on human chromosome 2p13-14. Fuchs S, et al. BMC Genet, 2002 Aug 13. PMID 12174196, Free PMC Article
    2. Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression. Naba A, et al. Sci Rep, 2017 Jan 10. PMID 28071719, Free PMC Article
    3. The level of the transcription factor Pax6 is essential for controlling the balance between neural stem cell self-renewal and neurogenesis. Sansom SN, et al. PLoS Genet, 2009 Jun. PMID 19521500, Free PMC Article
    4. Global discovery of erythroid long noncoding RNAs reveals novel regulators of red cell maturation. Alvarez-Dominguez JR, et al. Blood, 2014 Jan 23. PMID 24200680, Free PMC Article
    5. Widespread and dynamic translational control of red blood cell development. Alvarez-Dominguez JR, et al. Blood, 2017 Feb 2. PMID 27899360, Free PMC Article

    See all (23) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables carbohydrate binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in collagen-containing extracellular matrix HDA PubMed 

    General protein information

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    Preferred Names
    galectin-related protein
    Names
    galectin-related protein A
    lectin galactoside-binding-like protein A
    lectin, galactoside binding-like

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_173752.4 → NP_776113.1  galectin-related protein

      See identical proteins and their annotated locations for NP_776113.1

      Status: VALIDATED

      Source sequence(s)
      AK041053, AK081513, BE979710
      Consensus CDS
      CCDS24461.1
      UniProtKB/Swiss-Prot
      Q8C4P8, Q8VED9
      Related
      ENSMUSP00000044342.9, ENSMUST00000047028.9
      Conserved Domains (1) summary
      smart00908
      Location:46 → 170
      Gal-bind_lectin; Galactoside-binding lectin

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      20773355..20781916 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006514629.3 → XP_006514692.1  galectin-related protein isoform X2

      See identical proteins and their annotated locations for XP_006514692.1

      Conserved Domains (1) summary
      smart00908
      Location:38 → 162
      Gal-bind_lectin; Galactoside-binding lectin

    2. XM_030245782.2 → XP_030101642.1  galectin-related protein isoform X1

      Conserved Domains (1) summary
      smart00908
      Location:93 → 217
      Gal-bind_lectin; Galactoside-binding lectin
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8VED9.1 GenPept UniProtKB/Swiss-Prot:Q8VED9

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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