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    Crygn crystallin, gamma N [ Mus musculus (house mouse) ]

    Gene ID: 214301, updated on 21-Apr-2024

    Summary

    Official Symbol
    Crygnprovided by MGI
    Official Full Name
    crystallin, gamma Nprovided by MGI
    Primary source
    MGI:MGI:2449167
    See related
    Ensembl:ENSMUSG00000038135 AllianceGenome:MGI:2449167
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be a structural constituent of eye lens. Predicted to be involved in lens development in camera-type eye and visual perception. Is expressed in eyelid epithelium and lens. Orthologous to human CRYGN (crystallin gamma N). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
    NEW
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    Genomic context

    Location:
    5 A3; 5 11.93 cM
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 5 NC_000071.7 (24956000..24962846, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 5 NC_000071.6 (24751002..24757848, complement)

    Chromosome 5 - NC_000071.7Genomic Context describing neighboring genes Neighboring gene VISTA enhancer mm394 Neighboring gene negative regulator of ubiquitin-like proteins 1 Neighboring gene WD repeat domain 86 Neighboring gene STARR-seq mESC enhancer starr_12647 Neighboring gene STARR-seq mESC enhancer starr_12648 Neighboring gene predicted gene, 42231 Neighboring gene STARR-seq mESC enhancer starr_12649 Neighboring gene predicted gene, 33591 Neighboring gene STARR-positive B cell enhancer ABC_E666 Neighboring gene STARR-seq mESC enhancer starr_12651 Neighboring gene Ras homolog enriched in brain Neighboring gene protein kinase, AMP-activated, gamma 2 non-catalytic subunit Neighboring gene protein kinase, AMP-activated, gamma 2 non-catalytic subunit, opposite strand 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (3) 

    General gene information

    Markers

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables structural constituent of eye lens IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in lens development in camera-type eye IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in visual perception IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     

    General protein information

    Preferred Names
    gamma-crystallin N
    Names
    gamma-N-crystallin

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153076.3NP_694716.2  gamma-crystallin N

      See identical proteins and their annotated locations for NP_694716.2

      Status: VALIDATED

      Source sequence(s)
      AC137938, AF445456, CF738166
      Consensus CDS
      CCDS19129.1
      UniProtKB/Swiss-Prot
      Q0IJ73, Q0VAU5, Q8VHL5
      Related
      ENSMUSP00000035860.5, ENSMUST00000047119.5
      Conserved Domains (1) summary
      pfam00030
      Location:788
      Crystall; Beta/Gamma crystallin

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000071.7 Reference GRCm39 C57BL/6J

      Range
      24956000..24962846 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)