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    Fam83f family with sequence similarity 83, member F [ Mus musculus (house mouse) ]

    Gene ID: 213956, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Fam83fprovided by MGI
    Official Full Name
    family with sequence similarity 83, member Fprovided by MGI
    Primary source
    MGI:MGI:2146227
    See related
    Ensembl:ENSMUSG00000022408 AllianceGenome:MGI:2146227
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable protein kinase binding activity. Predicted to be involved in signal transduction. Is expressed in alimentary system; lower urinary tract; sensory organ; and vibrissa. Orthologous to human FAM83F (family with sequence similarity 83 member F). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in colon adult (RPKM 8.0), large intestine adult (RPKM 6.2) and 14 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    15 E1; 15 37.89 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (80555829..80584626)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (80671847..80700425)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene ENTH domain containing 1 Neighboring gene predicted gene, 19141 Neighboring gene STARR-seq mESC enhancer starr_39234 Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:80402055-80402238 Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:80402767-80403020 Neighboring gene STARR-seq mESC enhancer starr_39235 Neighboring gene GRB2-related adaptor protein 2 Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:80460969-80461152 Neighboring gene STARR-positive B cell enhancer ABC_E942 Neighboring gene STARR-seq mESC enhancer starr_39236 Neighboring gene STARR-seq mESC enhancer starr_39237 Neighboring gene microRNA 6957 Neighboring gene RIKEN cDNA A430088P11 gene Neighboring gene STARR-positive B cell enhancer ABC_E608 Neighboring gene STARR-seq mESC enhancer starr_39239 Neighboring gene STARR-positive B cell enhancer ABC_E9421 Neighboring gene trinucleotide repeat containing 6b Neighboring gene STARR-seq mESC enhancer starr_39241 Neighboring gene STARR-positive B cell enhancer ABC_E7395 Neighboring gene STARR-seq mESC enhancer starr_39242 Neighboring gene CapStarr-seq enhancer MGSCv37_chr15:80645405-80645514 Neighboring gene STARR-seq mESC enhancer starr_39245 Neighboring gene STARR-seq mESC enhancer starr_39246 Neighboring gene microRNA 5113 Neighboring gene predicted gene 6612 Neighboring gene adenylosuccinate lyase

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Genome-wide expression profiling of mid-gestation placenta and embryo using a 15,000 mouse developmental cDNA microarray. Tanaka TS, et al. Proc Natl Acad Sci U S A, 2000 Aug 1. PMID 10922068, Free PMC Article
    2. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    3. Normalization and subtraction: two approaches to facilitate gene discovery. Bonaldo MF, et al. Genome Res, 1996 Sep. PMID 8889548
    4. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    5. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073

    See all (13) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC27770

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein kinase binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Process Evidence Code Pubs
    involved_in signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein FAM83F

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001416208.1 → NP_001403137.1  protein FAM83F isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC147041

    2. NM_145986.3 → NP_666098.2  protein FAM83F isoform 1

      See identical proteins and their annotated locations for NP_666098.2

      Status: VALIDATED

      Source sequence(s)
      AC147041
      Consensus CDS
      CCDS49672.1
      UniProtKB/Swiss-Prot
      Q3UKU4, Q8C578, Q8CDC4, Q8R3Z0
      UniProtKB/TrEMBL
      A0A0R4J033
      Related
      ENSMUSP00000023044.6, ENSMUST00000023044.7
      Conserved Domains (3) summary
      cd09186
      Location:20 → 289
      PLDc_FAM83F_N; N-terminal phospholipase D-like domain of the uncharacterized protein, Family with sequence similarity 83F
      pfam13091
      Location:148 → 285
      PLDc_2; PLD-like domain
      pfam16000
      Location:379 → 472
      CARMIL_C; CARMIL C-terminus

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      80555829..80584626
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036159308.1 → XP_036015201.1  protein FAM83F isoform X1

      Conserved Domains (1) summary
      cl15239
      Location:1 → 127
      PLDc_SF; Catalytic domain of phospholipase D superfamily proteins

    2. XM_036159306.1 → XP_036015199.1  protein FAM83F isoform X1

      Conserved Domains (1) summary
      cl15239
      Location:1 → 127
      PLDc_SF; Catalytic domain of phospholipase D superfamily proteins
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q3UKU4.1 GenPept UniProtKB/Swiss-Prot:Q3UKU4

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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