Map9 microtubule-associated protein 9 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Map9provided by MGI
Official Full Name: microtubule-associated protein 9provided by MGI
Primary source: MGI:MGI:2442208
See related: Ensembl:ENSMUSG00000033900 AllianceGenome:MGI:2442208
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: ASAP; Mtap9; 5033421J10Rik; 5330427D05Rik
Summary: Predicted to enable microtubule binding activity. Acts upstream of or within mitotic spindle assembly. Located in astral microtubule and mitotic spindle midzone. Orthologous to human MAP9 (microtubule associated protein 9). [provided by Alliance of Genome Resources, Apr 2022]
Expression: Biased expression in CNS E18 (RPKM 17.3), cortex adult (RPKM 9.4) and 9 other tissues See more
Orthologs: human all
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Genomic context

Location:: 3 E3; 3 36.37 cM

Exon count:: 15

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	3	NC_000069.7 (82265379..82302575)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	3	NC_000069.6 (82358072..82395268)

Chromosome 3 - NC_000069.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

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See details

Project title: Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

MAP9 Loss Triggers Chromosomal Instability, Initiates Colorectal Tumorigenesis, and Is Associated with Poor Survival of Patients with Colorectal Cancer.
Title: MAP9 Loss Triggers Chromosomal Instability, Initiates Colorectal Tumorigenesis, and Is Associated with Poor Survival of Patients with Colorectal Cancer.

Submit: New GeneRIF Correction

Variation

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Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Targeted (2) 1 citation
Endonuclease-mediated (1)

Interactions

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Products	Interactant	Other Gene	Complex	Source	Pubs	Description

General gene information

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Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables microtubule binding	IBA Inferred from Biological aspect of Ancestor more info
enables microtubule binding	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within cell cycle	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within cell division	IEA Inferred from Electronic Annotation more info
involved_in mitotic cytokinesis	IEA Inferred from Electronic Annotation more info
involved_in mitotic spindle assembly	IBA Inferred from Biological aspect of Ancestor more info
acts_upstream_of_or_within mitotic spindle assembly	IDA Inferred from Direct Assay more info	PubMed
involved_in mitotic spindle assembly	ISO Inferred from Sequence Orthology more info
involved_in regulation of mitotic centrosome separation	ISO Inferred from Sequence Orthology more info
involved_in regulation of mitotic cytokinesis	IBA Inferred from Biological aspect of Ancestor more info
involved_in regulation of mitotic cytokinesis	ISO Inferred from Sequence Orthology more info
involved_in regulation of mitotic spindle organization	ISO Inferred from Sequence Orthology more info
involved_in spindle assembly	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in aster	IDA Inferred from Direct Assay more info	PubMed
is_active_in astral microtubule	IBA Inferred from Biological aspect of Ancestor more info
located_in astral microtubule	IDA Inferred from Direct Assay more info	PubMed
located_in astral microtubule	ISO Inferred from Sequence Orthology more info
located_in axon	ISO Inferred from Sequence Orthology more info
located_in cytoplasm	ISO Inferred from Sequence Orthology more info
located_in cytoskeleton	IEA Inferred from Electronic Annotation more info
located_in microtubule	IEA Inferred from Electronic Annotation more info
located_in microtubule cytoskeleton	IDA Inferred from Direct Assay more info	PubMed
located_in mitotic spindle	IDA Inferred from Direct Assay more info	PubMed
located_in mitotic spindle	ISO Inferred from Sequence Orthology more info
located_in mitotic spindle midzone	IDA Inferred from Direct Assay more info	PubMed
located_in spindle midzone	ISO Inferred from Sequence Orthology more info

General protein information

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Preferred Names: microtubule-associated protein 9

Names: aster-associated protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001081230.1 → NP_001074699.1 microtubule-associated protein 9

See identical proteins and their annotated locations for NP_001074699.1

Status: VALIDATED

Source sequence(s)

AC126248, AC126557

Consensus CDS

CCDS38461.1

UniProtKB/Swiss-Prot

Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7

UniProtKB/TrEMBL

A0A0A6YXJ3

Related

ENSMUSP00000088535.5, ENSMUST00000091014.10

Conserved Domains (1) summary

PTZ00121
Location:445 → 622

PTZ00121; MAEBL; Provisional
NM_001356457.1 → NP_001343386.1 microtubule-associated protein 9

Status: VALIDATED

Source sequence(s)

AC126248, AC126557, AK147287

Consensus CDS

CCDS38461.1

UniProtKB/Swiss-Prot

Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7

UniProtKB/TrEMBL

A0A0A6YXJ3

Related

ENSMUSP00000142206.2, ENSMUST00000195640.2

Conserved Domains (1) summary

PTZ00121
Location:445 → 622

PTZ00121; MAEBL; Provisional

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000069.7 Reference GRCm39 C57BL/6J

Range

82265379..82302575

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_030252539.2 → XP_030108399.1 microtubule-associated protein 9 isoform X1

UniProtKB/Swiss-Prot

Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7

UniProtKB/TrEMBL

A0A0A6YXJ3

Conserved Domains (1) summary

PTZ00121
Location:445 → 622

PTZ00121; MAEBL; Provisional
XM_030252540.2 → XP_030108400.1 microtubule-associated protein 9 isoform X1

UniProtKB/Swiss-Prot

Q3TRR0, Q3UUD1, Q3UX85, Q3UXE7, Q5M8N8, Q6P8K1, Q8BMM4, Q8BYP7

UniProtKB/TrEMBL

A0A0A6YXJ3

Conserved Domains (1) summary

PTZ00121
Location:445 → 622

PTZ00121; MAEBL; Provisional