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    Tfdp2 transcription factor Dp 2 [ Mus musculus (house mouse) ]

    Gene ID: 211586, updated on 11-Apr-2024

    Summary

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    Official Symbol
    Tfdp2provided by MGI
    Official Full Name
    transcription factor Dp 2provided by MGI
    Primary source
    MGI:MGI:107167
    See related
    Ensembl:ENSMUSG00000032411 AllianceGenome:MGI:107167
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    DP3; DP-3; 1110029I05Rik; A330080J22Rik
    Summary
    Enables DNA-binding transcription factor activity. Acts upstream of or within regulation of transcription, DNA-templated. Predicted to be located in mitotic spindle and nucleoplasm. Predicted to be part of RNA polymerase II transcription regulator complex. Predicted to be active in nucleus. Is expressed in several structures, including brain; early conceptus; genitourinary system; gut; and sensory organ. Orthologous to human TFDP2 (transcription factor Dp-2). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in liver E14 (RPKM 17.0), liver E14.5 (RPKM 15.8) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Tfdp2 in Genome Data Viewer
    Location:
    9 E3.3; 9 50.31 cM
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 9 NC_000075.7 (96078348..96205699)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 9 NC_000075.6 (96196246..96323646)

    Chromosome 9 - NC_000075.7Genomic Context describing neighboring genes Neighboring gene STARR-positive B cell enhancer ABC_E3852 Neighboring gene STARR-positive B cell enhancer ABC_E8307 Neighboring gene STARR-seq mESC enhancer starr_24940 Neighboring gene 5'-3' exoribonuclease 1 Neighboring gene STARR-seq mESC enhancer starr_24941 Neighboring gene STARR-seq mESC enhancer starr_24942 Neighboring gene STARR-positive B cell enhancer ABC_E8308 Neighboring gene glycerol kinase 5 Neighboring gene STARR-seq mESC enhancer starr_24949 Neighboring gene predicted gene, 39408 Neighboring gene ATPase, Na+/K+ transporting, beta 3 polypeptide Neighboring gene predicted gene, 39409 Neighboring gene predicted gene, 40550

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Global analysis of induced transcription factors and cofactors identifies Tfdp2 as an essential coregulator during terminal erythropoiesis. Chen C, et al. Exp Hematol, 2014 Jun. PMID 24607859, Free PMC Article
    2. A new member of the DP family, DP-3, with distinct protein products suggests a regulatory role for alternative splicing in the cell cycle transcription factor DRTF1/E2F. Ormondroyd E, et al. Oncogene, 1995 Oct 19. PMID 7478568
    3. Bone Marrow Mesenchymal Stem Cells Ameliorate Cisplatin-Induced Renal Fibrosis via miR-146a-5p/Tfdp2 Axis in Renal Tubular Epithelial Cells. Wu L, et al. Front Immunol, 2020. PMID 33664736, Free PMC Article
    4. Dp1 is largely dispensable for embryonic development. Kohn MJ, et al. Mol Cell Biol, 2004 Aug. PMID 15282318, Free PMC Article
    5. Genomic structure and developmental expression of the mouse cell cycle regulatory transcription factor DP1. Gopalkrishnan RV, et al. Oncogene, 1996 Dec 19. PMID 9000141

    See all (38) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. Bone Marrow Mesenchymal Stem Cells Ameliorate Cisplatin-Induced Renal Fibrosis via miR-146a-5p/Tfdp2 Axis in Renal Tubular Epithelial Cells.
      Title: Bone Marrow Mesenchymal Stem Cells Ameliorate Cisplatin-Induced Renal Fibrosis via miR-146a-5p/Tfdp2 Axis in Renal Tubular Epithelial Cells.
    2. TFDP2 is a critical cofactor required for proper cell cycle control and gene expression
      Title: Global analysis of induced transcription factors and cofactors identifies Tfdp2 as an essential coregulator during terminal erythropoiesis.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (2) 
    • Endonuclease-mediated (2) 

    Pathways from PubChem

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    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    contributes_to DNA-binding transcription activator activity, RNA polymerase II-specific ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to RNA polymerase II transcription regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    contributes_to RNA polymerase II transcription regulatory region sequence-specific DNA binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    		 PubMed 
    enables protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    enables transcription factor binding ISO
    Inferred from Sequence Orthology
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in negative regulation of DNA-templated transcription ISO
    Inferred from Sequence Orthology
    more info
    		  
    involved_in positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
    		  
    acts_upstream_of_or_within regulation of DNA-templated transcription IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    involved_in regulation of cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    Component Evidence Code Pubs
    part_of RNA polymerase II transcription regulator complex ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in mitotic spindle ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nuclear envelope TAS
    Traceable Author Statement
    more info
    		 PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
    		  
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    part_of transcription regulator complex IC
    Inferred by Curator
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    transcription factor Dp-2
    Names
    E2F dimerization partner 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001184706.2 → NP_001171635.1  transcription factor Dp-2 isoform 1

      See identical proteins and their annotated locations for NP_001171635.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1, 2, and 3 all encode the same isoform (1, also known as A).
      Source sequence(s)
      AC117248, AC166175
      Consensus CDS
      CCDS23413.1
      UniProtKB/TrEMBL
      F7AYT3, Q8BHD2, Q8C537
      Related
      ENSMUSP00000034982.10, ENSMUST00000034982.16
      Conserved Domains (3) summary
      cd14458
      Location:152 → 198
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:68 → 147
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:154 → 292
      DP; Transcription factor DP

    2. NM_001184708.2 → NP_001171637.1  transcription factor Dp-2 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks several alternate exon and uses a downstream start codon, compared to variant 1. The resulting isoform (2, also known as B) has a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AC117248, AC166175
      Consensus CDS
      CCDS52893.1
      UniProtKB/TrEMBL
      E9PWL5, Q8C8M7
      Related
      ENSMUSP00000132934.3, ENSMUST00000165120.9
      Conserved Domains (3) summary
      cd14458
      Location:77 → 123
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:1 → 72
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:79 → 218
      DP; Transcription factor DP

    3. NM_001184709.1 → NP_001171638.1  transcription factor Dp-2 isoform 1

      See identical proteins and their annotated locations for NP_001171638.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and represents use of an alternate promoter, compared to variant 1. Variants 1, 2, and 3 all encode the same isoform (1, also known as A).
      Source sequence(s)
      AC117248, AK033356, CJ141709
      Consensus CDS
      CCDS23413.1
      UniProtKB/TrEMBL
      F7AYT3, Q8BHD2, Q8C537
      Related
      ENSMUSP00000137176.2, ENSMUST00000179416.8
      Conserved Domains (3) summary
      cd14458
      Location:152 → 198
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:68 → 147
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:154 → 292
      DP; Transcription factor DP

    4. NM_001184710.2 → NP_001171639.1  transcription factor Dp-2 isoform 3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) represents use of an alternate promoter, differs in the 5' UTR, lacks an alternate exon, and uses a downstream start codon, compared to variant 1. The resulting isoform (3, also known as C) has a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AC117248, AC166175
      Consensus CDS
      CCDS52892.1
      UniProtKB/TrEMBL
      J3QK26, Q3TY79
      Related
      ENSMUSP00000136817.2, ENSMUST00000179065.8
      Conserved Domains (3) summary
      cd14458
      Location:126 → 172
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:42 → 121
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:128 → 267
      DP; Transcription factor DP

    5. NM_001184711.2 → NP_001171640.1  transcription factor Dp-2 isoform 4

      See identical proteins and their annotated locations for NP_001171640.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) represents use of an alternate promoter, differs in the 5' UTR, and uses an alternate in-frame splice site in the coding region, compared to variant 1. The resulting isoform (4, also known as D) includes an extra one amino acid segment, compared to isoform 1.
      Source sequence(s)
      AC117248, AC166175
      Consensus CDS
      CCDS57690.1
      UniProtKB/TrEMBL
      F6QG91, Q8C537
      Related
      ENSMUSP00000128260.3, ENSMUST00000165768.4
      Conserved Domains (3) summary
      cd14458
      Location:153 → 199
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:68 → 148
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:155 → 293
      DP; Transcription factor DP

    6. NM_001408517.1 → NP_001395446.1  transcription factor Dp-2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      F7AYT3, Q8BHD2

    7. NM_001408518.1 → NP_001395447.1  transcription factor Dp-2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      F7AYT3, Q8BHD2

    8. NM_001408519.1 → NP_001395448.1  transcription factor Dp-2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      F7AYT3, Q8BHD2

    9. NM_001408520.1 → NP_001395449.1  transcription factor Dp-2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      F7AYT3, Q8BHD2

    10. NM_001408521.1 → NP_001395450.1  transcription factor Dp-2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      F7AYT3, Q8BHD2

    11. NM_001408522.1 → NP_001395451.1  transcription factor Dp-2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      F7AYT3, Q8BHD2

    12. NM_001408523.1 → NP_001395452.1  transcription factor Dp-2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      F7AYT3, Q8BHD2

    13. NM_001408524.1 → NP_001395453.1  transcription factor Dp-2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      F7AYT3, Q8BHD2

    14. NM_001408525.1 → NP_001395454.1  transcription factor Dp-2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      F7AYT3, Q8BHD2

    15. NM_001408526.1 → NP_001395455.1  transcription factor Dp-2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      F7AYT3, Q8BHD2

    16. NM_001408527.1 → NP_001395456.1  transcription factor Dp-2 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      F7AYT3, Q8BHD2

    17. NM_001408528.1 → NP_001395457.1  transcription factor Dp-2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      E9PWL5

    18. NM_001408529.1 → NP_001395458.1  transcription factor Dp-2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      E9PWL5

    19. NM_001408530.1 → NP_001395459.1  transcription factor Dp-2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      E9PWL5

    20. NM_001408531.1 → NP_001395460.1  transcription factor Dp-2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      E9PWL5

    21. NM_001408532.1 → NP_001395461.1  transcription factor Dp-2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      E9PWL5

    22. NM_001408533.1 → NP_001395462.1  transcription factor Dp-2 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      E9PWL5

    23. NM_001408534.1 → NP_001395463.1  transcription factor Dp-2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      J3QK26

    24. NM_001408535.1 → NP_001395464.1  transcription factor Dp-2 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      J3QK26

    25. NM_001408536.1 → NP_001395465.1  transcription factor Dp-2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      F6QG91

    26. NM_001408537.1 → NP_001395466.1  transcription factor Dp-2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      F6QG91

    27. NM_001408538.1 → NP_001395467.1  transcription factor Dp-2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      F6QG91

    28. NM_001408539.1 → NP_001395468.1  transcription factor Dp-2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      F6QG91

    29. NM_001408540.1 → NP_001395469.1  transcription factor Dp-2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      F6QG91

    30. NM_001408541.1 → NP_001395470.1  transcription factor Dp-2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      F6QG91

    31. NM_001408542.1 → NP_001395471.1  transcription factor Dp-2 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      F6QG91

    32. NM_001408543.1 → NP_001395472.1  transcription factor Dp-2 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    33. NM_001408544.1 → NP_001395473.1  transcription factor Dp-2 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      UniProtKB/TrEMBL
      A0A087WPU8
      Related
      ENSMUSP00000139926.2, ENSMUST00000188750.7

    34. NM_001408545.1 → NP_001395474.1  transcription factor Dp-2 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    35. NM_001408546.1 → NP_001395475.1  transcription factor Dp-2 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    36. NM_001408547.1 → NP_001395476.1  transcription factor Dp-2 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    37. NM_001408548.1 → NP_001395477.1  transcription factor Dp-2 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    38. NM_001408549.1 → NP_001395478.1  transcription factor Dp-2 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    39. NM_001408550.1 → NP_001395479.1  transcription factor Dp-2 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    40. NM_001408551.1 → NP_001395480.1  transcription factor Dp-2 isoform 13

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    41. NM_001408552.1 → NP_001395481.1  transcription factor Dp-2 isoform 14

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    42. NM_001408553.1 → NP_001395482.1  transcription factor Dp-2 isoform 15

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    43. NM_001408554.1 → NP_001395483.1  transcription factor Dp-2 isoform 16

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    44. NM_001408555.1 → NP_001395484.1  transcription factor Dp-2 isoform 16

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    45. NM_001408556.1 → NP_001395485.1  transcription factor Dp-2 isoform 16

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      Related
      ENSMUSP00000139848.2, ENSMUST00000188008.7

    46. NM_001408557.1 → NP_001395486.1  transcription factor Dp-2 isoform 16

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    47. NM_001408558.1 → NP_001395487.1  transcription factor Dp-2 isoform 16

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    48. NM_001408559.1 → NP_001395488.1  transcription factor Dp-2 isoform 16

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175
      Related
      ENSMUSP00000141084.2, ENSMUST00000189606.7

    49. NM_001408560.1 → NP_001395489.1  transcription factor Dp-2 isoform 16

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    50. NM_001408561.1 → NP_001395490.1  transcription factor Dp-2 isoform 17

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    51. NM_001408562.1 → NP_001395491.1  transcription factor Dp-2 isoform 17

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    52. NM_001408563.1 → NP_001395492.1  transcription factor Dp-2 isoform 17

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    53. NM_001408564.1 → NP_001395493.1  transcription factor Dp-2 isoform 17

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    54. NM_001408565.1 → NP_001395494.1  transcription factor Dp-2 isoform 17

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    55. NM_001408566.1 → NP_001395495.1  transcription factor Dp-2 isoform 17

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    56. NM_001408567.1 → NP_001395496.1  transcription factor Dp-2 isoform 17

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    57. NM_001408568.1 → NP_001395497.1  transcription factor Dp-2 isoform 17

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    58. NM_001408569.1 → NP_001395498.1  transcription factor Dp-2 isoform 18

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    59. NM_001408570.1 → NP_001395499.1  transcription factor Dp-2 isoform 18

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    60. NM_001408571.1 → NP_001395500.1  transcription factor Dp-2 isoform 18

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    61. NM_001408572.1 → NP_001395501.1  transcription factor Dp-2 isoform 19

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    62. NM_001408573.1 → NP_001395502.1  transcription factor Dp-2 isoform 20

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    63. NM_001408574.1 → NP_001395503.1  transcription factor Dp-2 isoform 20

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    64. NM_001408575.1 → NP_001395504.1  transcription factor Dp-2 isoform 21

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    65. NM_001408576.1 → NP_001395505.1  transcription factor Dp-2 isoform 22

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    66. NM_001408577.1 → NP_001395506.1  transcription factor Dp-2 isoform 22

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    67. NM_001408578.1 → NP_001395507.1  transcription factor Dp-2 isoform 22

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    68. NM_001408579.1 → NP_001395508.1  transcription factor Dp-2 isoform 22

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    69. NM_001408580.1 → NP_001395509.1  transcription factor Dp-2 isoform 23

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    70. NM_001408581.1 → NP_001395510.1  transcription factor Dp-2 isoform 23

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    71. NM_001408582.1 → NP_001395511.1  transcription factor Dp-2 isoform 23

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    72. NM_001408583.1 → NP_001395512.1  transcription factor Dp-2 isoform 23

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    73. NM_001408584.1 → NP_001395513.1  transcription factor Dp-2 isoform 23

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    74. NM_001408585.1 → NP_001395514.1  transcription factor Dp-2 isoform 24

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    75. NM_001408586.1 → NP_001395515.1  transcription factor Dp-2 isoform 25

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    76. NM_001408587.1 → NP_001395516.1  transcription factor Dp-2 isoform 25

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    77. NM_001408588.1 → NP_001395517.1  transcription factor Dp-2 isoform 25

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    78. NM_001408589.1 → NP_001395518.1  transcription factor Dp-2 isoform 25

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    79. NM_001408590.1 → NP_001395519.1  transcription factor Dp-2 isoform 25

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    80. NM_001408591.1 → NP_001395520.1  transcription factor Dp-2 isoform 26

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    81. NM_001408592.1 → NP_001395521.1  transcription factor Dp-2 isoform 26

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    82. NM_001408593.1 → NP_001395522.1  transcription factor Dp-2 isoform 26

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    83. NM_001408594.1 → NP_001395523.1  transcription factor Dp-2 isoform 27

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    84. NM_001408595.1 → NP_001395524.1  transcription factor Dp-2 isoform 27

      Status: VALIDATED

      Source sequence(s)
      AC117248, AC166175

    85. NM_178667.5 → NP_848782.2  transcription factor Dp-2 isoform 1

      See identical proteins and their annotated locations for NP_848782.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform 1, also known as A. Variants 1, 2, and 3 all encode the same isoform.
      Source sequence(s)
      AC117248, AC166175
      Consensus CDS
      CCDS23413.1
      UniProtKB/TrEMBL
      F7AYT3, Q8BHD2, Q8C537
      Related
      ENSMUSP00000140061.2, ENSMUST00000185644.7
      Conserved Domains (3) summary
      cd14458
      Location:152 → 198
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:68 → 147
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:154 → 292
      DP; Transcription factor DP

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000075.7 Reference GRCm39 C57BL/6J

      Range
      96078348..96205699
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036154781.1 → XP_036010674.1  transcription factor Dp-2 isoform X11

      UniProtKB/TrEMBL
      F7AYT3, Q8BHD2, Q8C537
      Conserved Domains (3) summary
      cd14458
      Location:152 → 198
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:68 → 147
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:154 → 292
      DP; Transcription factor DP

    2. XM_036154779.1 → XP_036010672.1  transcription factor Dp-2 isoform X10

      UniProtKB/TrEMBL
      F6QG91, Q8C537
      Conserved Domains (3) summary
      cd14458
      Location:153 → 199
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:68 → 148
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:155 → 293
      DP; Transcription factor DP

    3. XM_036154778.1 → XP_036010671.1  transcription factor Dp-2 isoform X10

      UniProtKB/TrEMBL
      F6QG91, Q8C537
      Conserved Domains (3) summary
      cd14458
      Location:153 → 199
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:68 → 148
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:155 → 293
      DP; Transcription factor DP

    4. XM_030244201.1 → XP_030100061.1  transcription factor Dp-2 isoform X15

      UniProtKB/TrEMBL
      Q8C8M7
      Conserved Domains (3) summary
      cd14458
      Location:101 → 147
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:16 → 96
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:103 → 241
      DP; Transcription factor DP

    5. XM_030244202.1 → XP_030100062.1  transcription factor Dp-2 isoform X15

      UniProtKB/TrEMBL
      Q8C8M7
      Conserved Domains (3) summary
      cd14458
      Location:101 → 147
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:16 → 96
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:103 → 241
      DP; Transcription factor DP

    6. XM_006510981.4 → XP_006511044.1  transcription factor Dp-2 isoform X15

      See identical proteins and their annotated locations for XP_006511044.1

      UniProtKB/TrEMBL
      Q8C8M7
      Conserved Domains (3) summary
      cd14458
      Location:101 → 147
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:16 → 96
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:103 → 241
      DP; Transcription factor DP

    7. XM_006510974.3 → XP_006511037.1  transcription factor Dp-2 isoform X10

      See identical proteins and their annotated locations for XP_006511037.1

      UniProtKB/TrEMBL
      F6QG91, Q8C537
      Conserved Domains (3) summary
      cd14458
      Location:153 → 199
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:68 → 148
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:155 → 293
      DP; Transcription factor DP

    8. XM_036154782.1 → XP_036010675.1  transcription factor Dp-2 isoform X15

      UniProtKB/TrEMBL
      Q8C8M7
      Conserved Domains (3) summary
      cd14458
      Location:101 → 147
      DP_DD; coiled coil [structural motif]
      pfam02319
      Location:16 → 96
      E2F_TDP; E2F/DP family winged-helix DNA-binding domain
      pfam08781
      Location:103 → 241
      DP; Transcription factor DP
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q64163.2 GenPept UniProtKB/Swiss-Prot:Q64163

    Gene LinkOut

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