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    Ppp1r36 protein phosphatase 1, regulatory subunit 36 [ Mus musculus (house mouse) ]

    Gene ID: 210762, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Ppp1r36provided by MGI
    Official Full Name
    protein phosphatase 1, regulatory subunit 36provided by MGI
    Primary source
    MGI:MGI:2684916
    See related
    Ensembl:ENSMUSG00000052221 AllianceGenome:MGI:2684916
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm70
    Summary
    Predicted to enable phosphatase binding activity and protein phosphatase inhibitor activity. Predicted to be involved in negative regulation of phosphatase activity. Orthologous to human PPP1R36 (protein phosphatase 1 regulatory subunit 36). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in testis adult (RPKM 18.2), bladder adult (RPKM 2.4) and 1 other tissue See more
    Orthologs
    human all
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    Genomic context

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    Location:
    12 C3; 12 33.73 cM
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (76464267..76486266)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (76417493..76439492)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 25 Neighboring gene RIKEN cDNA 4930426I24 gene Neighboring gene zinc finger and BTB domain containing 1 Neighboring gene STARR-positive B cell enhancer ABC_E94 Neighboring gene STARR-seq mESC enhancer starr_32522 Neighboring gene heat shock protein 2 Neighboring gene predicted gene, 25563 Neighboring gene Ppp1r36 downstream neighbor Neighboring gene STARR-positive B cell enhancer ABC_E7147 Neighboring gene predicted gene, 40445

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. ILDR2 stabilization is regulated by its interaction with GRP78. Watanabe K, et al. Sci Rep, 2021 Apr 16. PMID 33863978, Free PMC Article
    2. Tissue expression patterns identify mouse cilia genes. McClintock TS, et al. Physiol Genomics, 2008 Jan 17. PMID 17971504
    3. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    4. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636
    5. RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. Shibata K, et al. Genome Res, 2000 Nov. PMID 11076861, Free PMC Article

    See all (10) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (3) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables phosphatase binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables protein phosphatase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in negative regulation of phosphatase activity IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  

    General protein information

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    Preferred Names
    protein phosphatase 1 regulatory subunit 36

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001163103.1 → NP_001156575.1  protein phosphatase 1 regulatory subunit 36

      See identical proteins and their annotated locations for NP_001156575.1

      Status: VALIDATED

      Source sequence(s)
      AC124453, AV274491, AV283991, CK137158
      Consensus CDS
      CCDS49093.1
      UniProtKB/Swiss-Prot
      D3Z0R2
      Related
      ENSMUSP00000069849.8, ENSMUST00000063977.9
      Conserved Domains (1) summary
      pfam14895
      Location:67 → 400
      PPPI_inhib; Protein phosphatase 1 inhibitor

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      76464267..76486266
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011244053.3 → XP_011242355.1  protein phosphatase 1 regulatory subunit 36 isoform X1

      Conserved Domains (1) summary
      pfam14895
      Location:13 → 244
      PPPI_inhib; Protein phosphatase 1 inhibitor

    RNA

    1. XR_003950023.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    D3Z0R2.1 GenPept UniProtKB/Swiss-Prot:D3Z0R2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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