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    Iglon5 IgLON family member 5 [ Mus musculus (house mouse) ]

    Gene ID: 210094, updated on 23-Mar-2024

    Summary

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    Official Symbol
    Iglon5provided by MGI
    Official Full Name
    IgLON family member 5provided by MGI
    Primary source
    MGI:MGI:2686277
    See related
    Ensembl:ENSMUSG00000013367 AllianceGenome:MGI:2686277
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Gm1431; A230106M20Rik
    Summary
    Predicted to be located in extracellular region. Is expressed in central nervous system; ganglia; and neural retina. Orthologous to human IGLON5 (IgLON family member 5). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in whole brain E14.5 (RPKM 27.1), CNS E14 (RPKM 23.2) and 14 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    7 B3; 7 28.25 cM
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (43122325..43139635, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (43472901..43490211, complement)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene electron transferring flavoprotein, beta polypeptide Neighboring gene microRNA 7051 Neighboring gene STARR-positive B cell enhancer ABC_E4923 Neighboring gene predicted gene, 39000 Neighboring gene V-set and immunoglobulin domain containing 10 like Neighboring gene Siglec family like 2 Neighboring gene predicted gene 9278

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Spatiotemporal expression of IgLON family members in the developing mouse nervous system. Fearnley S, et al. Sci Rep, 2021 Oct 1. PMID 34599206, Free PMC Article
    2. Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion. Gu Z, et al. PLoS One, 2015. PMID 25826454, Free PMC Article
    3. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article
    4. Antisense transcription in the mammalian transcriptome. Katayama S, et al. Science, 2005 Sep 2. PMID 16141073
    5. High-efficiency full-length cDNA cloning. Carninci P, et al. Methods Enzymol, 1999. PMID 10349636

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. IgLON5 deficiency produces behavioral alterations in a knockout mouse model.
      Title: IgLON5 deficiency produces behavioral alterations in a knockout mouse model.
    Submit: New GeneRIF Correction

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (4) 

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    igLON family member 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001164518.2 → NP_001157990.1  igLON family member 5 precursor

      See identical proteins and their annotated locations for NP_001157990.1

      Status: VALIDATED

      Source sequence(s)
      AC154108
      Consensus CDS
      CCDS52223.1
      UniProtKB/Swiss-Prot
      A7E1X9, Q8HW98
      Related
      ENSMUSP00000103608.2, ENSMUST00000107974.3
      Conserved Domains (3) summary
      pfam13927
      Location:217 → 295
      Ig_3; Immunoglobulin domain
      cd00096
      Location:41 → 46
      Ig; Ig strand A' [structural motif]
      cl11960
      Location:41 → 129
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      43122325..43139635 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_003946429.1 RNA Sequence

    2. XR_003946430.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8HW98.2 GenPept UniProtKB/Swiss-Prot:Q8HW98

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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