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    Slc35f3 solute carrier family 35, member F3 [ Mus musculus (house mouse) ]

    Gene ID: 210027, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Slc35f3provided by MGI
    Official Full Name
    solute carrier family 35, member F3provided by MGI
    Primary source
    MGI:MGI:2444426
    See related
    Ensembl:ENSMUSG00000057060 AllianceGenome:MGI:2444426
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    B230375D17Rik
    Summary
    Predicted to be involved in thiamine transport. Predicted to be located in membrane. Predicted to be integral component of membrane. Orthologous to human SLC35F3 (solute carrier family 35 member F3). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in large intestine adult (RPKM 19.1), ovary adult (RPKM 16.7) and 28 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    8 E2; 8 73.82 cM
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (126865155..127122726)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (126138398..126395987)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene potassium channel, subfamily K, member 1 Neighboring gene STARR-seq mESC enhancer starr_23054 Neighboring gene STARR-seq mESC enhancer starr_23055 Neighboring gene predicted gene, 53470 Neighboring gene predicted gene, 46072 Neighboring gene predicted gene, 31165 Neighboring gene STARR-seq mESC enhancer starr_23057 Neighboring gene ribosomal protein S2 pseudogene Neighboring gene STARR-seq mESC enhancer starr_23059 Neighboring gene STARR-positive B cell enhancer ABC_E8274 Neighboring gene predicted gene, 51604 Neighboring gene predicted gene, 51604 Neighboring gene TAR RNA binding protein 1 Neighboring gene cytochrome c oxidase assembly factor 6

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    2. GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Visel A, et al. Nucleic Acids Res, 2004 Jan 1. PMID 14681479, Free PMC Article
    3. BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. Magdaleno S, et al. PLoS Biol, 2006 Apr. PMID 16602821, Free PMC Article
    4. A conditional knockout resource for the genome-wide study of mouse gene function. Skarnes WC, et al. Nature, 2011 Jun 15. PMID 21677750, Free PMC Article
    5. A high-resolution anatomical atlas of the transcriptome in the mouse embryo. Diez-Roux G, et al. PLoS Biol, 2011 Jan 18. PMID 21267068, Free PMC Article

    See all (14) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC141263, MGC141264

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in thiamine transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  
    involved_in thiamine transport ISO
    Inferred from Sequence Orthology
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    solute carrier family 35 member F3
    Names
    putative thiamine transporter SLC35F3
    thiamine transporter SLC35F3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001363500.1 → NP_001350429.1  solute carrier family 35 member F3 isoform 1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the longer isoform (1).
      Source sequence(s)
      AC122236, AC125192
      UniProtKB/TrEMBL
      A0A571BEK8
      Related
      ENSMUSP00000158727.2, ENSMUST00000238518.2
      Conserved Domains (2) summary
      pfam06027
      Location:215 → 388
      SLC35F; Solute carrier family 35
      pfam00892
      Location:118 → 273
      EamA; EamA-like transporter family

    2. NM_175434.3 → NP_780643.2  solute carrier family 35 member F3 isoform 2

      See identical proteins and their annotated locations for NP_780643.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR and coding sequence compared to variant 1. The resulting isoform (2) has a shorter and distinct N-terminus compared to isoform 1.
      Source sequence(s)
      AC122236, BB318499, BC115965, CJ057689
      Consensus CDS
      CCDS40520.1
      UniProtKB/Swiss-Prot
      Q1LZI2, Q8BL51
      UniProtKB/TrEMBL
      A0A571BEK8
      Related
      ENSMUSP00000104390.3, ENSMUST00000108759.3
      Conserved Domains (1) summary
      pfam00892
      Location:67 → 223
      EamA; EamA-like transporter family

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      126865155..127122726
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011248334.3 → XP_011246636.1  solute carrier family 35 member F3 isoform X1

      UniProtKB/TrEMBL
      A0A571BEK8
      Conserved Domains (2) summary
      pfam06027
      Location:215 → 388
      SLC35F; Solute carrier family 35
      pfam00892
      Location:118 → 273
      EamA; EamA-like transporter family

    2. XM_030243383.2 → XP_030099243.1  solute carrier family 35 member F3 isoform X5

    3. XM_030243382.1 → XP_030099242.1  solute carrier family 35 member F3 isoform X3

      Conserved Domains (1) summary
      cl28899
      Location:8 → 49
      DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily

    4. XM_011248335.3 → XP_011246637.1  solute carrier family 35 member F3 isoform X4

      Conserved Domains (1) summary
      cl28899
      Location:8 → 49
      DEAD-like_helicase_N; N-terminal helicase domain of the DEAD-box helicase superfamily

    5. XM_030243381.2 → XP_030099241.1  solute carrier family 35 member F3 isoform X2

      UniProtKB/TrEMBL
      A0A571BFY6
      Conserved Domains (1) summary
      pfam06027
      Location:73 → 182
      SLC35F; Solute carrier family 35

    6. XM_006530806.4 → XP_006530869.1  solute carrier family 35 member F3 isoform X2

      See identical proteins and their annotated locations for XP_006530869.1

      UniProtKB/TrEMBL
      A0A571BFY6
      Conserved Domains (1) summary
      pfam06027
      Location:73 → 182
      SLC35F; Solute carrier family 35
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q1LZI2.1 GenPept UniProtKB/Swiss-Prot:Q1LZI2

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