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    Smagp small cell adhesion glycoprotein [ Mus musculus (house mouse) ]

    Gene ID: 207818, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Smagpprovided by MGI
    Official Full Name
    small cell adhesion glycoproteinprovided by MGI
    Primary source
    MGI:MGI:2448476
    See related
    Ensembl:ENSMUSG00000053559 AllianceGenome:MGI:2448476
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be located in cell junction; nucleoplasm; and plasma membrane. Is expressed in alimentary system; genitourinary system; hindlimb mesenchyme; skeleton; and skin. Orthologous to human SMAGP (small cell adhesion glycoprotein). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in colon adult (RPKM 168.3), duodenum adult (RPKM 139.4) and 14 other tissues See more
    Orthologs
    human all
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    Genomic context

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    See Smagp in Genome Data Viewer
    Location:
    15 F1; 15 56.37 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (100519220..100534821, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (100621339..100636940, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene RIKEN cDNA C330013E15 gene Neighboring gene STARR-positive B cell enhancer ABC_E610 Neighboring gene DAZ associated protein 2 Neighboring gene bridging integrator 2 Neighboring gene microRNA 6961 Neighboring gene STARR-positive B cell enhancer ABC_E311 Neighboring gene chymotrypsin-like elastase family, member 1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. SMAGP, a new small trans-membrane glycoprotein altered in cancer. Tarbé NG, et al. Oncogene, 2004 Apr 22. PMID 15021913
    2. Osteoblast-specific expression of Panx3 is dispensable for postnatal bone remodeling. Yorgan TA, et al. Bone, 2019 Oct. PMID 31202927
    3. Database resources of the National Center for Biotechnology Information. Wheeler DL, et al. Nucleic Acids Res, 2001 Jan 1. PMID 11125038, Free PMC Article
    4. The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Koscielny G, et al. Nucleic Acids Res, 2014 Jan. PMID 24194600, Free PMC Article
    5. EUCOMM--the European conditional mouse mutagenesis program. Friedel RH, et al. Brief Funct Genomic Proteomic, 2007 Sep. PMID 17967808

    See all (15) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 
    • Endonuclease-mediated (1) 

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC7903

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in cytoplasmic vesicle IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
    		  
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
    		  
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
    		  

    General protein information

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    Preferred Names
    small cell adhesion glycoprotein
    Names
    small cell transmembrane and glycosylated protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001033872.2 → NP_001029044.1  small cell adhesion glycoprotein isoform 1

      See identical proteins and their annotated locations for NP_001029044.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Both variants 1 and 2 encode the same isoform (1).
      Source sequence(s)
      BG067486, BX635258, CJ042753, CJ053067
      Consensus CDS
      CCDS27842.1
      UniProtKB/Swiss-Prot
      Q99KC7
      Related
      ENSMUSP00000126870.2, ENSMUST00000172334.9

    2. NM_001285413.1 → NP_001272342.1  small cell adhesion glycoprotein isoform 2

      See identical proteins and their annotated locations for NP_001272342.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in its 5' UTR, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. Both variants 3 and 4 encode the same isoform.
      Source sequence(s)
      BG067486, BX635258, CJ052873
      Consensus CDS
      CCDS88847.1
      UniProtKB/TrEMBL
      A0A2R8W734
      Related
      ENSMUSP00000155534.2, ENSMUST00000230517.2

    3. NM_001285414.1 → NP_001272343.1  small cell adhesion glycoprotein isoform 2

      See identical proteins and their annotated locations for NP_001272343.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in its 5' UTR, and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus, compared to isoform 1. Both variants 3 and 4 encode the same isoform.
      Source sequence(s)
      BG067486, BX635258, CJ052870, CJ052873
      Consensus CDS
      CCDS88847.1
      UniProtKB/TrEMBL
      A0A2R8W734
      Related
      ENSMUSP00000155782.2, ENSMUST00000229307.2

    4. NM_174992.4 → NP_778157.2  small cell adhesion glycoprotein isoform 1

      See identical proteins and their annotated locations for NP_778157.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (1). Both variants 1 and 2 encode the same isoform.
      Source sequence(s)
      AC123724, BG067486, BX635258, CJ042753, CJ053067, CJ065989
      Consensus CDS
      CCDS27842.1
      UniProtKB/Swiss-Prot
      Q99KC7
      Related
      ENSMUSP00000066137.6, ENSMUST00000066068.7

    RNA

    1. NR_104337.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) uses alternate splice sites in the 5' and 3'-terminal exons, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
      Source sequence(s)
      BE132795, BG067486, BX635258, CJ053067

    2. NR_104338.1 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) uses an alternate splice site in the 3'-terminal exon, compared to variant 1. This variant is represented as non-coding because the predicted protein does not meet RefSeq quality criteria.
      Source sequence(s)
      AC123724, BE132795, BG067486, BX635258, CJ042753, CJ053067, CJ065989

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      100519220..100534821 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q99KC7.2 GenPept UniProtKB/Swiss-Prot:Q99KC7

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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