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    Mucl2 mucin-like 2 [ Mus musculus (house mouse) ]

    Gene ID: 20770, updated on 8-Feb-2024

    Summary

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    Official Symbol
    Mucl2provided by MGI
    Official Full Name
    mucin-like 2provided by MGI
    Primary source
    MGI:MGI:98392
    See related
    Ensembl:ENSMUSG00000036925 AllianceGenome:MGI:98392
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Spt1; Spt-1
    Summary
    Predicted to be located in extracellular region. Is expressed in thymus and thymus primordium. Orthologous to human MUCL1 (mucin like 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Low expression observed in reference dataset See more
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    Genomic context

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    Location:
    15 F3; 15
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (103926121..103929578, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (103895855..103899312, complement)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene mucin-like 1 Neighboring gene predicted gene, 21178

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. A new member of the hormonally regulated rodent submaxillary gland glycoprotein gene family: cDNA cloning and tissue specific expression. Myal Y, et al. Mol Cell Endocrinol, 1996 Jul 1. PMID 8832572
    2. Molecular cloning of cDNAs from androgen-independent mRNA species of DBA/2 mouse sub-maxillary glands. Windass JD, et al. Nucleic Acids Res, 1984 Feb 10. PMID 6546617, Free PMC Article
    3. Rapid evolution of variants in a rodent multigene family encoding salivary proteins. Dickinson DP, et al. Mol Biol Evol, 1989 Jan. PMID 2921944
    4. Genetic and tissue-specific variation in the expression of a closely linked murine multigene family on chromosome 15 that encodes salivary and lacrimal proteins. Dickinson DP, et al. Biochem Genet, 1989 Oct. PMID 2482730
    5. Modulation of Aire regulates the expression of tissue-restricted antigens. Kont V, et al. Mol Immunol, 2008 Jan. PMID 17599412, Free PMC Article

    See all (17) citations in PubMed

    GeneRIFs: Gene References Into Functions

    General gene information

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    Markers

    Homology

    Clone Names

    • MGC29130, MGC118102

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
    		  
    located_in extracellular region IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    mucin-like protein 2
    Names
    16.5 kDa submandibular gland glycoprotein
    salivary protein 1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_009267.2 → NP_033293.2  mucin-like protein 2 precursor

      See identical proteins and their annotated locations for NP_033293.2

      Status: VALIDATED

      Source sequence(s)
      CK616337, CK616968
      Consensus CDS
      CCDS57015.1
      UniProtKB/Swiss-Prot
      P02815, Q3KQK8, Q62263, Q9DA65
      Related
      ENSMUSP00000044814.7, ENSMUST00000037685.9
      Conserved Domains (1) summary
      COG4547
      Location:20 → 137
      CobT2; Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphorib... [Coenzyme transport and metabolism]

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      103926121..103929578 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036159293.1 → XP_036015186.1  mucin-like protein 2 isoform X1

      UniProtKB/TrEMBL
      A0A2I3BRY2
      Related
      ENSMUSP00000154772.2, ENSMUST00000226584.2
      Conserved Domains (1) summary
      PRK08581
      Location:9 → 128
      PRK08581; amidase domain-containing protein
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P02815.2 GenPept UniProtKB/Swiss-Prot:P02815

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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