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    Fam120c family with sequence similarity 120, member C [ Mus musculus (house mouse) ]

    Gene ID: 207375, updated on 5-Mar-2024

    Summary

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    Official Symbol
    Fam120cprovided by MGI
    Official Full Name
    family with sequence similarity 120, member Cprovided by MGI
    Primary source
    MGI:MGI:2387687
    See related
    Ensembl:ENSMUSG00000025262 AllianceGenome:MGI:2387687
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    ORF34; D930001I21Rik
    Summary
    Predicted to be active in nucleus. Is expressed in brain; embryo; skeletal muscle; and testis. Orthologous to human FAM120C (family with sequence similarity 120C). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in frontal lobe adult (RPKM 4.9), cerebellum adult (RPKM 4.3) and 27 other tissues See more
    Orthologs
    human all
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    Genomic context

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    Location:
    X F3; X 68.46 cM
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCm39 (GCF_000001635.27) X NC_000086.8 (150125515..150257135)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) X NC_000086.7 (151342519..151474139)

    Chromosome X - NC_000086.8Genomic Context describing neighboring genes Neighboring gene WNK lysine deficient protein kinase 3 Neighboring gene predicted gene, 26441 Neighboring gene RIKEN cDNA A230072E10 gene Neighboring gene STARR-positive B cell enhancer mm9_chrX:147778291-147778592 Neighboring gene importin 5 pseudogene Neighboring gene predicted gene, 22248 Neighboring gene NSA2 ribosome biogenesis homolog pseudogene Neighboring gene STARR-seq mESC enhancer starr_48081 Neighboring gene ribosomal protein L39 pseudogene Neighboring gene predicted gene, 24460 Neighboring gene PHD finger protein 8

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Expression

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    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

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    Related articles in PubMed

    1. Heparanase alters arterial structure, mechanics, and repair following endovascular stenting in mice. Baker AB, et al. Circ Res, 2009 Feb 13. PMID 19096032, Free PMC Article
    2. The human gene CXorf17 encodes a member of a novel family of putative transmembrane proteins: cDNA cloning and characterization of CXorf17 and its mouse ortholog orf34. Holden S, et al. Gene, 2003 Oct 30. PMID 14585507
    3. Ex vivo Quantitative Proteomic Analysis of Serotonin Transporter Interactome: Network Impact of the SERT Ala56 Coding Variant. Quinlan MA, et al. Front Mol Neurosci, 2020. PMID 32581705, Free PMC Article
    4. New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules. Das R, et al. J Cell Sci, 2019 Jun 17. PMID 31138677, Free PMC Article
    5. Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics. Federspiel JD, et al. Mol Cell Proteomics, 2019 Aug 9. PMID 31040226, Free PMC Article

    See all (19) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Variation

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    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (3) 

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
    		  
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
    		  
    Component Evidence Code Pubs
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    		  

    General protein information

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    Preferred Names
    constitutive coactivator of PPAR-gamma-like protein 2
    Names
    family with sequence similarity 120C

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_198105.2 → NP_932773.2  constitutive coactivator of PPAR-gamma-like protein 2

      See identical proteins and their annotated locations for NP_932773.2

      Status: VALIDATED

      Source sequence(s)
      AK030477, AK136727, AL662922
      Consensus CDS
      CCDS41175.1
      UniProtKB/Swiss-Prot
      Q3U0F6, Q8C3F2
      UniProtKB/TrEMBL
      B7ZW94
      Related
      ENSMUSP00000073082.6, ENSMUST00000073364.6

    RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000086.8 Reference GRCm39 C57BL/6J

      Range
      150125515..150257135
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011247802.4 → XP_011246104.1  constitutive coactivator of PPAR-gamma-like protein 2 isoform X1

      Conserved Domains (2) summary
      pfam08549
      Location:426 → 460
      SWI-SNF_Ssr4; Fungal domain of unknown function (DUF1750)
      cl28905
      Location:5 → 276
      PIN_SF; PIN (PilT N terminus) domain: Superfamily

    2. XM_030251275.2 → XP_030107135.1  constitutive coactivator of PPAR-gamma-like protein 2 isoform X2

    RNA

    1. XR_004940330.1 RNA Sequence

    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q8C3F2.3 GenPept UniProtKB/Swiss-Prot:Q8C3F2

    Gene LinkOut

    The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

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